马梅 蓝雪霏

    【摘要】 目的：探讨氟哌噻吨美利曲辛片联合埃索美拉唑、莫沙必利治疗慢性胃炎(chronic gastritis，CG)患者的效果。方法：选取2019年8月-2020年8月于广东医科大学附属第三医院确诊并治疗的66例

    CG患者，按随机数字表法将其分为对照组与研究组，每組33例。对照组应用埃索美拉唑、莫沙必利治疗，研究组在对照组基础上联合氟哌噻吨美利曲辛片治疗。比较两组治疗前与治疗7、14 d后胃肠道症状分级(GSRS-C)评分;比较两组治疗前后相关胃电参数指标[主频(DF)、餐后/餐前的主功率之比(PR)、主功率(DP)、正常慢波节律百分比(N%)]、焦虑自评量表(self-rating anxiety scale，SAS)与抑郁自评量表(self-rating depression scale，SDS)评分。结果：治疗7、14 d后，研究组GSRS-C评分均低于对照组(P<0.05)。治疗后，研究组相关胃电参数指标均高于对照组(P<0.05)。研究组治疗后SDS及SAS评分均低于对照组(P<0.05)。结论：氟哌噻吨美利曲辛片联合埃索美拉唑、莫沙必利可显著改善CG患者的胃电参数、胃肠道及抑郁焦虑症状。

    【关键词】 慢性胃炎 氟哌噻吨美利曲辛片 埃索美拉唑 莫沙必利 胃电参数

    Effect of Flupentixol and Melitracen Tablets Combined with Esomeprazole and Mosapride in the Treatment of Chronic Gastritis/MA Mei， LAN Xuefei. //Medical Innovation of China， 2022， 19(01)： 0-052

    [Abstract] Objective： To explore the efficacy of Flupentixol and Melitracen Tablets combined with Esomeprazole and Mosapride in the treatment of patients with chronic gastritis (CG). Method： A total of 66 CG patients diagnosed and treated in the Third Affiliated Hospital of Guangdong Medical University from August 2019 to August 2020 were selected. They were divided into control group and study group according to random number table method ......