余新莲 李艳琼 李晓芹 梁斐 黄清苑

    【摘要】 目的：分析中藥自拟方在气虚质封闭抗体阴性复发性流产(RSA)治疗中的应用效果。方法：本次研究对象来源于梅州市人民医院2019年1月-2021年9月确诊的80例气虚质封闭抗体阴性RSA患者，根据抽签法分为观察组与对照组，每组40例。对照组接受淋巴细胞主动免疫治疗及黄体支持治疗，观察组在对照组基础上接受中药自拟方治疗。对比两组封闭抗体转阳率、妊娠率、流产率、活胎分娩率及不良反应发生率。结果：观察组封闭抗体转阳率为75.00%(30/40)，高于对照组52.50%(21/40)，差异有统计学意义(P<0.05)。观察组妊娠率、活胎分娩率均高于对照组，流产率低于对照组(P<0.05)。两组不良反应发生率比较，差异无统计学意义(P>0.05)。结论：自拟益气补虚、培补脾肾方可有效提高气虚质封闭抗体阴性RSA患者封闭抗体转阳率、妊娠率、活胎分娩率，降低流产率，且无明显不良反应，安全性较高。

    【关键词】 中药自拟方 气虚质 封闭抗体阴性 复发性流产

    Clinical Observation of Traditional Chinese Medicine Intervention on Recurrent Spontaneous Abortion with Negative Blocking Antibody due to Qi Deficiency/YU Xinlian， LI Yanqiong， LI Xiaoqin， LIANG Fei， HUANG Qingyuan. //Medical Innovation of China， 2022， 19(13)： 0-074

    [Abstract] Objective： To analyze the application effect of self-made prescription of traditional Chinese medicine in the treatment of recurrent spontaneous abortion (RSA) with negative blocking antibody due to Qi deficiency. Method： The subjects of this study were from 80 patients with RSA with negative blocking antibody due to Qi deficiency in Meizhou People’s Hospital from January 2019 to September 2021. They were divided into the control group and the observation group according to the lottery method ......