范建平 林梅珊

    【摘要】 目的：觀察腹腔镜微创术联合葛根芩连汤加减对结直肠癌(CRC)患者免疫功能的影响。方法：选取2020年3月-2022年6月江西中医药大学第二附属医院收治的79例CRC患者，根据入院门诊单双号分组，A组(单号，40例)、B组(双号，39例)。A组患者接受腹腔镜微创术，B组在A组基础上联合葛根芩连汤加减治疗。比较两组免疫功能(CD3+、CD4+、CD8+)、炎症因子指标[白细胞介素-6(IL-6)、C反应蛋白(CRP)、白细胞介素-10(IL-10)]及并发症发生率。结果：治疗后，两组CD3+、CD4+水平均较治疗前升高，CD8+水平较治疗前下降，且B组CD3+、CD4+均高于A组，CD8+低于A组，差异均有统计学意义(P0.05)。结论：腹腔镜微创术联合葛根芩连汤加减应用于CRC患者中，可降低炎症因子水平，提高患者免疫功能。

    【关键词】 结直肠癌 腹腔镜微创术 葛根芩连汤加减

    [Abstract] Objective： To observe the effect of laparoscopic minimally invasive surgery combined with modified Gegen Qinlian Decoction on immune function in patients with colorectal cancer (CRC). Method： A total of 79 CRC patients who were admitted to the Second Affiliated Hospital of Jiangxi University TCM from March 2020 to June 2022 were selected， they were divided into group A (40 patients with single number) and group B (39 patients with double number) according to the single and double number groups of the inpatients. The patients in group A received laparoscopic minimally invasive surgery ......