贾富华 武书丽

    【摘要】 儿童肥胖与维生素D缺乏(VDD)已成为国内外严重的公共卫生问题。肥胖儿童的VDD是容积稀释、脂肪固存、代谢性脂肪肝、维生素D剂服用率低等多因素作用的结果。VDD能够干预脂肪组织新陈代谢、瘦素水平等，成为肥胖的危险因素之一。对VDD进行干预对于减少体脂的作用尚未明确，但与正常儿童相比，肥胖儿童需要补充更高剂量的维生素D才能达到充足的血清浓度。本文就儿童肥胖与VDD的联系、肥胖儿童VDD推荐治疗剂量结合目前研究进行综述。

    【关键词】 维生素D缺乏 儿童肥胖 25-羟维生素D 剂量

    Research Progress of Childhood Obesity and Vitamin D Deficiency/JIA Fuhua， WU Shuli. //Medical Innovation of China， 2023， 20(35)： -172

    [Abstract] Childhood obesity and Vitamin D deficiency (VDD) have become serious public health problems at home and abroad. VDD in obese children is the result of multiple factors such as volume dilution， fat retention， metabolic fatty liver and low vitamin D dosage rate. VDD can interfere with adipose tissue metabolism and leptin level， and become one of the risk factors for obesity. The role of VDD intervention in reducing body fat is not clear， but obese children require higher doses of vitamin D supplementation to achieve adequate serum concentrations compared with normal children. In this article， the childhood obesity and VDD， obese children VDD recommended dosage treatment combined with the present study were reviewed. ......