GRK2在阿尔茨海默病发病机制中的作用(3)
[12]Sallese M,Salvatore L,DUrbano E,et al.The G-protein-coupled receptor kinase GRK4 mediates homologous desensitization of metabotropic glutamate receptor 1.FASEB J,2000,14:2569-2580.
[13]Lodowski DT,Pitcher JA,Capel WD,et al.Keeping G proteins at bay:a complex between G protein-coupled receptor kinase 2 and Gbetagamma.Science,2003,300:1256-1262.
[14]Theilade J,Strom C,Christiansen T,et al.Differential G protein receptor kinase 2 expression in compensated hypertrophy and heart failure after myocardial infarction in the rat.Basic Res Cardiol,2003,98:97-103.
, 百拇医药
[15]Tayor F Jr,Penela P,Ruiz-Gomez A.Role of G protein-coupled receptor kinase 2 and arrestins in beta-adrenergic receptor internalization.Trends Cardiovasc Med,1998,8:234-240.
[16]Kohout TA,Lefkowitz RJ.Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization.Mol Pharmacol,2003,63:9:18.
[17]Pitcher JA,Freedman NJ,Lefkowitz RJ.G protein-coupled receptor kinases.Annu Rev Biochem,1998,67:653-692.
, 百拇医药
[18]Ribas C,Penela P,Murga C,et al.The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling.Biochim Biophys Acta,2007,1768:913-922.
[19]Carman CV,Lisanti MP,Benovic JL.Regulation of G protein-coupled receptor kinases by caveolin. J Biol Chem,1999,274:8858-8864.
[20]Erdtmann-Vourliotis M,Mayer P,Ammon S,et al.Distribution of G-proteincoupled receptor kinase (GRK) isoforms 2,3,5 and 6 mRNA in the rat brain.Brain Res Mol Brain Res,2001,95:129-137.
, http://www.100md.com
[21]Obrenovich ME,Raina AK,Ogawa O,et al.Alzheimer disease - a new beginning,or a final exit? In:Nicoletti F,Copani A,editors.Cell-cycle mechanisms in neuronal death.Landes Biosciences Austin TX,2003:71-90.
[22]Obrenovich ME,Smith MA,Siedlak SL,et al.Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions.Neurotox Res,2006,10:43-56.
[23]Obrenovich MA,Raina AK,Ogawa O,et al.Alzheimer disease: a new beginning or a final exit?In: Copani A,Nicoletti F,editors.Cell cycle activation and cell death in the nervous system.Landes Biosciences Austin TX,2005:1-15.
, 百拇医药
[24]Sallese M,Iacovelli L,Cumashi A,et al.Regulation of G protein-coupled receptor kinase subtypes by calcium sensor proteins.Biochim Biophys Acta,2000,1498:112-121.
[25]Carman CV,Lisanti MP,Benovic JL.Regulation of G protein-coupled receptor kinases by caveolin. J Biol Chem,1999,274:8858-8864.
[26]Suo Z,Wu M,Citron BA,et al.Abnormality of G-protein-coupled receptor kinases at prodromal and early stages of Alzheimers disease: an association with early beta-amyloid accumulation. J Neurosci,2004,24:3444-3452.
, 百拇医药
[27]Obrenovich ME,Smith MA,Siedlak SL,et al.Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions.Neurotox Res,2006,10:43-56.
[28]Zhu X,Smith MA,Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. J Neurol Sci 2007;257,240-246., http://www.100md.com(王彦喆,孙景旭)
[13]Lodowski DT,Pitcher JA,Capel WD,et al.Keeping G proteins at bay:a complex between G protein-coupled receptor kinase 2 and Gbetagamma.Science,2003,300:1256-1262.
[14]Theilade J,Strom C,Christiansen T,et al.Differential G protein receptor kinase 2 expression in compensated hypertrophy and heart failure after myocardial infarction in the rat.Basic Res Cardiol,2003,98:97-103.
, 百拇医药
[15]Tayor F Jr,Penela P,Ruiz-Gomez A.Role of G protein-coupled receptor kinase 2 and arrestins in beta-adrenergic receptor internalization.Trends Cardiovasc Med,1998,8:234-240.
[16]Kohout TA,Lefkowitz RJ.Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization.Mol Pharmacol,2003,63:9:18.
[17]Pitcher JA,Freedman NJ,Lefkowitz RJ.G protein-coupled receptor kinases.Annu Rev Biochem,1998,67:653-692.
, 百拇医药
[18]Ribas C,Penela P,Murga C,et al.The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling.Biochim Biophys Acta,2007,1768:913-922.
[19]Carman CV,Lisanti MP,Benovic JL.Regulation of G protein-coupled receptor kinases by caveolin. J Biol Chem,1999,274:8858-8864.
[20]Erdtmann-Vourliotis M,Mayer P,Ammon S,et al.Distribution of G-proteincoupled receptor kinase (GRK) isoforms 2,3,5 and 6 mRNA in the rat brain.Brain Res Mol Brain Res,2001,95:129-137.
, http://www.100md.com
[21]Obrenovich ME,Raina AK,Ogawa O,et al.Alzheimer disease - a new beginning,or a final exit? In:Nicoletti F,Copani A,editors.Cell-cycle mechanisms in neuronal death.Landes Biosciences Austin TX,2003:71-90.
[22]Obrenovich ME,Smith MA,Siedlak SL,et al.Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions.Neurotox Res,2006,10:43-56.
[23]Obrenovich MA,Raina AK,Ogawa O,et al.Alzheimer disease: a new beginning or a final exit?In: Copani A,Nicoletti F,editors.Cell cycle activation and cell death in the nervous system.Landes Biosciences Austin TX,2005:1-15.
, 百拇医药
[24]Sallese M,Iacovelli L,Cumashi A,et al.Regulation of G protein-coupled receptor kinase subtypes by calcium sensor proteins.Biochim Biophys Acta,2000,1498:112-121.
[25]Carman CV,Lisanti MP,Benovic JL.Regulation of G protein-coupled receptor kinases by caveolin. J Biol Chem,1999,274:8858-8864.
[26]Suo Z,Wu M,Citron BA,et al.Abnormality of G-protein-coupled receptor kinases at prodromal and early stages of Alzheimers disease: an association with early beta-amyloid accumulation. J Neurosci,2004,24:3444-3452.
, 百拇医药
[27]Obrenovich ME,Smith MA,Siedlak SL,et al.Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions.Neurotox Res,2006,10:43-56.
[28]Zhu X,Smith MA,Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. J Neurol Sci 2007;257,240-246., http://www.100md.com(王彦喆,孙景旭)