阿立哌唑与利培酮治疗精神分裂症的对照研究(1)
 |
| 第1页 |
参见附件。
【摘要】目的评价阿立哌唑治疗精神分裂症的有效性和安全性。方法将64例精神分裂症患者随机分为阿立哌唑组32例和利培酮组32例,进行为期6周的随机双盲对照研究，采用阳性和阴性症状量表(PANSS)、治疗中出现的症状量表(TESS)及有关实验室检查评定疗效和安全性。结果治疗6周两组PANSS评分较治疗前均显著降低(均P<0.05),各时点PANSS评分两组间减分差异无统计学意义(P<0.05)。治疗6周末，两组间比较差异无统计学意义(P<0.05)。两组均未发生严重相关不良事件。结论阿立哌唑治疗精神分裂症的疗效与利培酮相当,是一种安全而有效的抗精神病药物。
【关键词】阿立哌唑；利培酮；精神分裂症
Randomized double blind control study of aripip razole and risperidone on the treatment of schizophrenia WU Yan-qing.Tianjin Anding Hospital,Tianjin 300222,China
【Abstract】ObjectiveTo assess the efficacy and safety of aripiprazole on the treatment of sch izophrenia.MethodsA randomized, double-blind, double -dummy,comparative study was performed with a course of 8 weeks.Sixty-four Patients with sch izophrenia were randomized into aripiprazole group(n= 32)and risperidone group(n=32).The positive and negative syndrome scale (PANSS),treatment emergent symptom scale (TESS) were used to asess the effectiveness and the safety of the treatment ......
您现在查看是摘要介绍页，详见PDF附件。