论文下载：自噬效应蛋白Beclin1的研究进展-凋亡-自噬基因

自噬效应蛋白Beclin1的研究进展(1)

http://www.100md.com 2011年10月5日黄蓉韦曦

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     【摘要】Beclin1是近年发现参与自噬调控的蛋白之一，与某些疾病如肿瘤等密切相关。本文通过介绍Beclin1的基本结构及相关自噬机制，总结了Beclin1在自噬、凋亡、肿瘤中的研究进展，并探讨其在细胞研究领域中的潜能。

    【关键词】自噬；凋亡；自噬基因；Beclin1

    Research progress of autophagy effector Beclin1 HUANG Rong,WEI Xi.Guanghua School of Stomatology,Sun Yat-Sen University,Guangzhou 510055,China

    【Abstract】Beclin1 is one of the proteins involved in the regulation of autophagy.It has been shown to be crucial for several diseases especially for cancer development.This review introduces the vital structure of Beclin1 and the mechanism of autophagy related to this protein.Also it summarizes the current research results that link disturbances in autophagy,apoptosis and tumor to Beclin1Finally it provides a brief overview of the existing exploration on Beclin1 and its potentiality in cell field ......

http://www.100md.com/html/paper/1674-6805/2011/28/131.htm

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