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编号:13759570
探讨维持性血透患者氧化应激状态及护理对策
http://www.100md.com 2011年11月5日 朱冬菊 周春
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     【摘要】目的研究维持性血透患者(MHD)体内的氧化应激状态及护理对策。方法选择2008年1月~2010年3月在攀枝花学院附属医院血液净化中心透析时间超过3个月的MHD患者48例,检测血浆中血浆丙二醛(MDA)、晚期氧化蛋白产物(AOPP)、过氧化物歧化酶(SOD)、谷光苷肽过氧化物酶(GSH-PX)等氧化指标。选择28名健康者作对照组。结果MHD患者,MDA、AOPP较对照组明显增高(P均<0.01),SOD及GSH-PX活性较对照组明显降低(P均<0.01)。MHD患者,Hb、ALB明显低于对照组(P<0.01)。结论血透患者体内存在明显的氧化应激状态,临床护理中可采取相应护理对策改善血透患者体内的氧化应激状态。

    【关键词】血液透析;氧化应激;护理

    Nursing care on oxidative stress in patient with MHD ZHU Dong-ju ,ZHOU Chun.Medical School of Panzhihua College,Panzhihua 617000,China

    【Abstract】ObjectiveTo investigate the effect of nusing care on oxidative stress in patient with MHD(maintenance hemodialysis).Methods38 patients with MHD and 20 healthy volunteers were involved in this study.malondialdehyde(MDA),advanced oxidation protein(AOPP),superoxide dismutase(SOD),activity of glutathione peroxidase(GSH-PX) in plasma were measured in patients and healthy voluteers.ResultsThe levels of plasma AOPP,MDA in MHD patients were higher than healthy volunteers (P<0.01) and SOD and GSH-PX were lower than healthy volunteers (P<0 ......

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