蛛网膜下腔出血后低钠血症与血浆心房钠尿肽的临床研究
蛛网膜下腔出血Clinical,research,on,atrial,natriuretic,pe
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【摘要】目的探讨血浆心房钠尿肽(ANP)与蛛网膜下腔出血(SAH)后低钠血症的关系及低钠血症与Fisher分级、Hunt-Hess分级的关系。方法动态测定60例SAH患者发病后第1～3天和第7天、第14天的血浆ANP、血钠水平，分析两者间的关系。结果在60例SAH患者中19例出现低钠血症，其血浆ANP水平高于健康对照组(P<0.05)；Fisher分级较差患者低钠血症发生率较高(P<0.05)；Hunt-Hess分级与低钠血症发生率有关(P<0.05)。结论ANP可能导致了SAH后的低钠血症，低钠血症可能与患者病情轻重和预后不良有关。
【关键词】低钠血症；心房钠尿肽；蛛网膜下腔出血Clinical research on atrial natriuretic peptide and hyponatremia after subarachnoid hemorrhage ZENG Huo-yong,CHENG Xiao-ying,LIANG Da-shun,TAN Xin.Guangdong Provincial Central Hospital of Reclamation,Zhanjiang 524002,China
【Abstract】ObjectiveTo investigate the plasma concentration of ANP,Fisher grade ,Hunt-Hess grade and their relationship with hyponatremia following SAH.MethodsPlasma ANP and serum sodium level were dynamic detected in the 60 cases of SAH patients after the onset of the first 1 to 3 days and 7 days,14 days,to analysis the relationship between them. ResultsIn 60 cases of SAH patients,46 cases of hyponatremia the plasma ANP level was higher(P<0.05),patients with poor Fisher grade were higher incidence of hyponatremia (P<0 ......
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