84例高危妊娠的临床研究(2)
妊娠合并糖尿病是一种内分泌代谢性疾病,病因未明,有遗传倾向。在胰岛素问世以前,糖尿病妇女妊娠甚为少见。由于胰岛素的应用,使糖尿病妇女的生育率接近正常[7]。据估计糖尿病患者合并妊娠的发生率为0.1%~2.7%。在胰岛素应用前,糖尿病孕妇死亡率为30%,而胰岛素的应用,极大地降低了孕妇死亡率,但较正常孕妇仍高20倍。糖尿病孕妇羊水过多、妊娠期高血压疾病发生率都较正常孕妇升高,孕妇一旦发生酮症酸中毒,胎儿死亡率高达85%~100%。
参考文献
[1] Macdonald I R,MacLennan H R.A consideration of the treatment of elderly primigravidae[J].J Obstet Gynecol Brit Emp,2012,167(12):443—446.
[2] Morrison I.The elderly primigravid[J].Am J Obstet Gynecol,2011,121(6):465—468.
[3] Anachebe J F,Sutton M Y.Racial disparities in reproductive health outcome[J].Am J Obstet Gynecol,2012,122(9):37—39.
[4] Cunningham F G,Leveno K J,Bloom S L,et al.Williams Obstetrics[M].22nd edition.New York:McGraw—Hill Medical Publishing Division,2012:6—46.
[5] Grimes D A,Gross G K.Pregnancy outcomes in black women aged 35 and older[J].Obstet Gynecol,2011,58(6):614—615.
[6] Kessler I,Lancet A M,Borenstein R,et al.The problem of the older primipara[J].Obstet Gynecol,2012,59(3):165—166.
[7] Kirz D S,Dorchester W,Freeman R K.Advanced matemal age:the mature gravida[J].Am J Obstet Gynecol,2012,122(3):7—10.
(收稿日期:2012—06—12) (编辑:何玉勤), http://www.100md.com(彭晓容)
参考文献
[1] Macdonald I R,MacLennan H R.A consideration of the treatment of elderly primigravidae[J].J Obstet Gynecol Brit Emp,2012,167(12):443—446.
[2] Morrison I.The elderly primigravid[J].Am J Obstet Gynecol,2011,121(6):465—468.
[3] Anachebe J F,Sutton M Y.Racial disparities in reproductive health outcome[J].Am J Obstet Gynecol,2012,122(9):37—39.
[4] Cunningham F G,Leveno K J,Bloom S L,et al.Williams Obstetrics[M].22nd edition.New York:McGraw—Hill Medical Publishing Division,2012:6—46.
[5] Grimes D A,Gross G K.Pregnancy outcomes in black women aged 35 and older[J].Obstet Gynecol,2011,58(6):614—615.
[6] Kessler I,Lancet A M,Borenstein R,et al.The problem of the older primipara[J].Obstet Gynecol,2012,59(3):165—166.
[7] Kirz D S,Dorchester W,Freeman R K.Advanced matemal age:the mature gravida[J].Am J Obstet Gynecol,2012,122(3):7—10.
(收稿日期:2012—06—12) (编辑:何玉勤), http://www.100md.com(彭晓容)