成骨细胞的应力信号通路研究进展(4)
[21] Hens J R，Wilson K M，Dann P，et al.TOPGAL mice show that the canonical Wnt signaling pathway is active during bone development and growth and is activated by mechanical loading in vitro[J].J Bone Miner Res，2005，20(7)：1103-1113.
[22] Johnson M L，Kamel M A.The Wnt signaling pathway and bone metabolism[J].Curr Opin Rheum，2007，19(4)：376-382.
[23] Lin C，Jiang X，Dai Z，et al.Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling[J].J Bone Miner Res，2009，24(10)：1651-1661.
[24] Qiu N，Xiao Z，Cao L，et al.Disruption of Kif3a in osteoblasts results in defective bone formation and osteopenia[J].J Cell Sci，2012，125(8)：1945-1957.
[25] Norvell S M，Alvarez M，Bidwell J P，et al.Fluid shear stress induces beta-catenin signaling in osteoblasts[J].Caleif Tissue Int，2004，75(5)：396-404.
[26] Robinson J A，Chatterjee-Kishore M，Yaworsky P J，et al.Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone[J].J Biol Chem，2006，281(42)：31720-31728.
[27] Jansen J H，Eijken M，Jahr H，et al.Stretch-induced inhibition of Wnt/ beta-catenin signaling in mineralizing osteoblasts[J].J Orthop Res，2010，28(3)：390-396.
[28] Barker N，Hurlstone A，Musisi H，et al.Thechromatin remodelling factor Brg-1 interacts with β-Catenin topromote target gene activation[J].Embo J，2002，20(17)：4935-4943.
(收稿日期：2014-07-24) (编辑：程旭然), http://www.100md.com(乐立盛 余光书)
[22] Johnson M L，Kamel M A.The Wnt signaling pathway and bone metabolism[J].Curr Opin Rheum，2007，19(4)：376-382.
[23] Lin C，Jiang X，Dai Z，et al.Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling[J].J Bone Miner Res，2009，24(10)：1651-1661.
[24] Qiu N，Xiao Z，Cao L，et al.Disruption of Kif3a in osteoblasts results in defective bone formation and osteopenia[J].J Cell Sci，2012，125(8)：1945-1957.
[25] Norvell S M，Alvarez M，Bidwell J P，et al.Fluid shear stress induces beta-catenin signaling in osteoblasts[J].Caleif Tissue Int，2004，75(5)：396-404.
[26] Robinson J A，Chatterjee-Kishore M，Yaworsky P J，et al.Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone[J].J Biol Chem，2006，281(42)：31720-31728.
[27] Jansen J H，Eijken M，Jahr H，et al.Stretch-induced inhibition of Wnt/ beta-catenin signaling in mineralizing osteoblasts[J].J Orthop Res，2010，28(3)：390-396.
[28] Barker N，Hurlstone A，Musisi H，et al.Thechromatin remodelling factor Brg-1 interacts with β-Catenin topromote target gene activation[J].Embo J，2002，20(17)：4935-4943.
(收稿日期：2014-07-24) (编辑：程旭然), http://www.100md.com(乐立盛 余光书)