颈动脉粥样硬化与冠状动脉病变程度的相关性研究(1)
【摘要】 目的：探讨颈动脉粥样硬化程度与冠状动脉病变程度的相关性。方法：随机选取2013年1-12月笔者所在医院收治的冠状动脉造影患者210例，根据患者的病变程度将其分为冠心病组(110例)和非冠心病组(100例)。对所有患者进行双侧颈动脉超声检查，测定患者的颈动脉病变程度，并对两组结果进行对比。结果：冠心病组患者的Crouse积分、斑块数目与等级积分分别为(3.67±3.10)分、(1.35±1.21)个与(2.20±1.96)分，各指标值均高于相应非冠心病组患者的(2.36±1.85)分、(0.96±0.81)个与(1.46±1.30)分，差异均有统计学意义(P<0.05)。两组患者各积分也随其病变狭窄程度的加重而增大，差异有统计学意义(P<0.001)。患者颈动脉斑块严重度与冠脉病变相关系数为0.396(P<0.05)。结论：颈动脉粥样硬化程度与冠状动脉狭窄程度之间呈正相关，对存在多种冠心病危险因素患者，进行常规颈动脉超声检查，可早期发现冠心病高危患者。
【关键词】 颈动脉粥样硬化； 冠脉病变； 颈动脉超声
中图分类号 R541.4 文献标识码 A 文章编号 1674-6805(2015)13-0006-03
Analysis the Correlations between Carotid Atherosclerosis and Extent and Severity of Coronary Artery Lesions/LI Li-jun，ZHAO Chang-jiao.//Chinese and Foreign Medical Research，2015，13(13)：6-8
【Abstract】 Objective：To analysis the correlations between carotid atherosclerosis and extent and severity of coronary artery lesions.Method：From January 2013 to December 2013，210 patients with coronary arteriography in our hospital were selected and divided into coronary heart disease group(n=110) and non coronary heart disease group (n=100) according to the degree of pathological changes.Did bilateral carotid ultrasound examination for all the patients to exam the patient’s carotid artery lesions.Then the results of two groups were compared.Result：The crouse integral，patch number and grade points were (3.67±3.10)，(1.35±1.21) and (2.20±1.96) in coronary heart disease group，which were higher than (2.36±1.85)，(0.96±0.81) and (1.46±1.30) in non coronary heart disease group(P<0.05).The integral narrow degree aggravating with the increase of its pathological changes and the results above were statistically significance(P<0.001).The correlation coefficient of carotid plaques severity and coronary lesions was 0.396(P<0.05).Conclusion：It has positive correlation between carotid plaques severity and coronary lesions.Do normal carotid ultrasound examination for the coronary heart disease patients with many risk factors can early detect the patients at high risk of coronary heart disease.
【Key words】 Carotid atherosclerosis； Coronary lesions； Carotid ultrasound
First-author’s address：Beijing Coal Group General Hospital，Beijing 102300，China
doi：10.14033/j.cnki.cfmr.2015.13.003
冠状动脉粥样硬化性心脏病(简称冠心病)，是临床常见的心脑血管疾病，发病原因主要为动脉粥样硬化[1]，患者动脉内膜最易受到影响，动脉内中膜增厚，严重者出现斑块状。研究显示，颈动脉粥样硬化与冠状动脉硬化具有相似的病理基础、发病因素以及发病机制[1-2]。动脉粥样硬化超声学改变表现为粥样斑块状和动脉内膜中层厚度(IMT)增加。IMT增厚是动脉粥样硬化的早期症状，影像中的斑块是其特征性表现，可以判断冠状动脉硬化的程度[3]。本研究旨在探讨颈动脉粥样硬化与冠状动脉病变程度的相关性，现报道如下。, 百拇医药(李利军 赵嫦姣)
【关键词】 颈动脉粥样硬化； 冠脉病变； 颈动脉超声
中图分类号 R541.4 文献标识码 A 文章编号 1674-6805(2015)13-0006-03
Analysis the Correlations between Carotid Atherosclerosis and Extent and Severity of Coronary Artery Lesions/LI Li-jun，ZHAO Chang-jiao.//Chinese and Foreign Medical Research，2015，13(13)：6-8
【Abstract】 Objective：To analysis the correlations between carotid atherosclerosis and extent and severity of coronary artery lesions.Method：From January 2013 to December 2013，210 patients with coronary arteriography in our hospital were selected and divided into coronary heart disease group(n=110) and non coronary heart disease group (n=100) according to the degree of pathological changes.Did bilateral carotid ultrasound examination for all the patients to exam the patient’s carotid artery lesions.Then the results of two groups were compared.Result：The crouse integral，patch number and grade points were (3.67±3.10)，(1.35±1.21) and (2.20±1.96) in coronary heart disease group，which were higher than (2.36±1.85)，(0.96±0.81) and (1.46±1.30) in non coronary heart disease group(P<0.05).The integral narrow degree aggravating with the increase of its pathological changes and the results above were statistically significance(P<0.001).The correlation coefficient of carotid plaques severity and coronary lesions was 0.396(P<0.05).Conclusion：It has positive correlation between carotid plaques severity and coronary lesions.Do normal carotid ultrasound examination for the coronary heart disease patients with many risk factors can early detect the patients at high risk of coronary heart disease.
【Key words】 Carotid atherosclerosis； Coronary lesions； Carotid ultrasound
First-author’s address：Beijing Coal Group General Hospital，Beijing 102300，China
doi：10.14033/j.cnki.cfmr.2015.13.003
冠状动脉粥样硬化性心脏病(简称冠心病)，是临床常见的心脑血管疾病，发病原因主要为动脉粥样硬化[1]，患者动脉内膜最易受到影响，动脉内中膜增厚，严重者出现斑块状。研究显示，颈动脉粥样硬化与冠状动脉硬化具有相似的病理基础、发病因素以及发病机制[1-2]。动脉粥样硬化超声学改变表现为粥样斑块状和动脉内膜中层厚度(IMT)增加。IMT增厚是动脉粥样硬化的早期症状，影像中的斑块是其特征性表现，可以判断冠状动脉硬化的程度[3]。本研究旨在探讨颈动脉粥样硬化与冠状动脉病变程度的相关性，现报道如下。, 百拇医药(李利军 赵嫦姣)
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