早期肠内营养联合血液净化治疗重症急性胰腺炎的临床观察(2)
综上所述，早期肠内营养与血液净化联用可减轻重症急性胰腺炎患者的炎症反应，维持肠道黏膜屏障完整。
参考文献
[1]中华医学会消化病学分会胰腺疾病学组.中国急性胰腺炎诊治指南(2013，上海)[J].中国实用内科杂志，2013，33(7)：530-535.
[2] Pastor C M，Vonlaufen A，Georgi F，et al.Neutrophil depletion-but not prevention of Kupffer cell activation-decreases the severity of cerulein-induced acute pancreatitis[J].World J Gastroenterol，2006，12(8)：1219-1224.
[3] Abdulla A，Awla D，Thorlacius H，et al.Role of neutrophils in the activation of trypsinogen in severe acute pancreatitis[J].Leukorc Biol，2011，90(5)：975-982.
[4] Medveczky P，Szmola R，Sahin-Toth M.Proteolytic activation of human pancreatitis-associated protein is required for peptidoglycan binding and bacterial aggregation[J].Biochem，2009，420(2)：335-343.
[5] Li X，Ma F，Jia K.Early enteral nutrition within 24 hours or between 24 and 72 hours for acute pancreatitis： evidence based on 12RCTs[J].Med Sci Monit，2014，27(20)：2327-2335.
[6]周俊杰，罗琼湘，章雄军，等.早期连续性血液净化治疗重症急性胰腺炎14例[J].世界华人消化杂志，2012，20(9)：800-803.
[7] Doig G S，Simpson F.Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition： a full economic analysis of a multicenter randomized controlled trial based on US costs[J].Clinicoecon Outcomes Res，2013，5(1)：369-379.
(收稿日期：2015-12-24), 百拇医药(肖宏 桂培根)
参考文献
[1]中华医学会消化病学分会胰腺疾病学组.中国急性胰腺炎诊治指南(2013，上海)[J].中国实用内科杂志，2013，33(7)：530-535.
[2] Pastor C M，Vonlaufen A，Georgi F，et al.Neutrophil depletion-but not prevention of Kupffer cell activation-decreases the severity of cerulein-induced acute pancreatitis[J].World J Gastroenterol，2006，12(8)：1219-1224.
[3] Abdulla A，Awla D，Thorlacius H，et al.Role of neutrophils in the activation of trypsinogen in severe acute pancreatitis[J].Leukorc Biol，2011，90(5)：975-982.
[4] Medveczky P，Szmola R，Sahin-Toth M.Proteolytic activation of human pancreatitis-associated protein is required for peptidoglycan binding and bacterial aggregation[J].Biochem，2009，420(2)：335-343.
[5] Li X，Ma F，Jia K.Early enteral nutrition within 24 hours or between 24 and 72 hours for acute pancreatitis： evidence based on 12RCTs[J].Med Sci Monit，2014，27(20)：2327-2335.
[6]周俊杰，罗琼湘，章雄军，等.早期连续性血液净化治疗重症急性胰腺炎14例[J].世界华人消化杂志，2012，20(9)：800-803.
[7] Doig G S，Simpson F.Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition： a full economic analysis of a multicenter randomized controlled trial based on US costs[J].Clinicoecon Outcomes Res，2013，5(1)：369-379.
(收稿日期：2015-12-24), 百拇医药(肖宏 桂培根)