输血前实施不规则抗体检测的意义和价值分析(1)
【摘要】 目的：研究输血前实施不规则抗体检测的意义和价值。方法：从2010年1月-2016年1月，笔者所在医院共有3498例病患需进行输血治疗，对所有患者输血前都给予不规则抗体检测，回顾性分析检测结果。结果：所有患者的结果表明，阳性者24例，其中男性阳性率为0.35%(6/1738)，女性阳性率为1.02%(18/1760)。女性阳性率显著高于男性。18例女性阳性患者中，非孕妇占0.52%(5/970)，孕妇占1.65%(13/790)。孕妇不规则抗体阳性率显著大于非孕妇，差异有统计学意义(P<0.05)。24例不规则抗体阳性患者中，抗-M占29.17%(7/24)，抗-D占25.00%(6/24)，抗-E占20.83%(5/24)，抗-C占16.67%(4/24)，非特异性抗体占8.33%(2/24)。结论：临床在对患者进行输血治疗前先实施不规则抗体检测有利于保证患者的输血安全，有效降低临床医疗事故。临床应加强孕产妇血液检测，有效控制新生儿出现溶血病。
【关键词】 输血； 不规则抗体； 检测；
, 百拇医药
doi：10.14033/j.cnki.cfmr.2016.31.027 文献标识码 B 文章编号 1674-6805(2016)31-0052-02
【Abstract】 Objective：To study significance and value of the detection of irregular antibodies before blood transfusion. Method：From January 2010 to January 2016，in the author’s hospital，a total of 3498 patients suffering from the need for blood transfusions were given irregular antibody screening of all patients before transfusion， the test results were analyzed retrospectively.Result：The results showed that all the patients，positive patients were a total of 24 cases，which male positive rate was 0.35% (6/1738).The positive rate of female was 1.02%(18/1760).The positive rate of female was significantly higher than that of male.In 18 women with positive，non pregnant women accounted for 0.52% (5/970)， pregnant women accounted for 1.65% (13/790) The positive rate of irregular antibody in pregnant women was significantly higher than that in non pregnant women，and the difference was statistically significant(P<0.05).Among 24 patients with irregular antibody positive，Anti-M was 29.17%(7/24)，Anti-D accounted for 25%(6/24)，Anti-E accounted for 20.83%(5/24)， Anti-C accounted for 16.67%(4/24)，nonspecific antibodies accounted for 8.33% (2/24).Conclusion： Clinical implementation before giving blood transfusions in patients with irregular antibody testing can ensure the patient’s blood transfusion safety，reduce clinical medical accidents.Clinical maternal blood tests should be strengthened，effectively control neonatal hemolytic disease.
, 百拇医药
【Key words】 Blood transfusion； Irregular antibody； detection； Value
First-author’s address：The First Affiliated Hospital of Sanming City of Fujian Medical University，Sanming 365000，China
輸血是临床比较常见的一种治疗方法，然而输血过程中可能会出现一种比较严重的并发症，溶血反应[1]。为了确保输血过程安全，须进行不规则抗体检测。不规则抗体在临床又名意外抗体，是血清中抗-A，抗-B和抗-AB之外的一种血型抗体[2]。急性溶血反应主要是因ABO血型之间不相容而引起，而主要危险因素为血液中的不规则抗体[3]。因此临床输血前除了要对患者进行血型鉴定还要对不规则抗体进行检测，以确保输血安全进行。本文通过分析对笔者所在医院输血患者实施不规则抗体检测的意义，旨在更好地服务临床诊断与治疗，现报道如下。
1 资料与方法
1.1 一般资料, 百拇医药(毛建玉 肖文海 叶祖兴)
【关键词】 输血； 不规则抗体； 检测；
, 百拇医药
doi：10.14033/j.cnki.cfmr.2016.31.027 文献标识码 B 文章编号 1674-6805(2016)31-0052-02
【Abstract】 Objective：To study significance and value of the detection of irregular antibodies before blood transfusion. Method：From January 2010 to January 2016，in the author’s hospital，a total of 3498 patients suffering from the need for blood transfusions were given irregular antibody screening of all patients before transfusion， the test results were analyzed retrospectively.Result：The results showed that all the patients，positive patients were a total of 24 cases，which male positive rate was 0.35% (6/1738).The positive rate of female was 1.02%(18/1760).The positive rate of female was significantly higher than that of male.In 18 women with positive，non pregnant women accounted for 0.52% (5/970)， pregnant women accounted for 1.65% (13/790) The positive rate of irregular antibody in pregnant women was significantly higher than that in non pregnant women，and the difference was statistically significant(P<0.05).Among 24 patients with irregular antibody positive，Anti-M was 29.17%(7/24)，Anti-D accounted for 25%(6/24)，Anti-E accounted for 20.83%(5/24)， Anti-C accounted for 16.67%(4/24)，nonspecific antibodies accounted for 8.33% (2/24).Conclusion： Clinical implementation before giving blood transfusions in patients with irregular antibody testing can ensure the patient’s blood transfusion safety，reduce clinical medical accidents.Clinical maternal blood tests should be strengthened，effectively control neonatal hemolytic disease.
, 百拇医药
【Key words】 Blood transfusion； Irregular antibody； detection； Value
First-author’s address：The First Affiliated Hospital of Sanming City of Fujian Medical University，Sanming 365000，China
輸血是临床比较常见的一种治疗方法，然而输血过程中可能会出现一种比较严重的并发症，溶血反应[1]。为了确保输血过程安全，须进行不规则抗体检测。不规则抗体在临床又名意外抗体，是血清中抗-A，抗-B和抗-AB之外的一种血型抗体[2]。急性溶血反应主要是因ABO血型之间不相容而引起，而主要危险因素为血液中的不规则抗体[3]。因此临床输血前除了要对患者进行血型鉴定还要对不规则抗体进行检测，以确保输血安全进行。本文通过分析对笔者所在医院输血患者实施不规则抗体检测的意义，旨在更好地服务临床诊断与治疗，现报道如下。
1 资料与方法
1.1 一般资料, 百拇医药(毛建玉 肖文海 叶祖兴)