抗病毒治疗在慢性乙型肝炎治疗中的临床效果分析(2)
综上,在慢性乙型肝炎治疗中应用恩替卡韦、拉米夫定+阿德福韦酯实施抗病毒治疗时,恩替卡韦在改善HBeAg、HBV-DNA阴转率以及ALT复常率方面的效果比较显著,还可以显著提高患者血清中IL-18以及IFN-γ,治疗效果显著,值得推广与应用。
参考文献
[1] Keeffe E B,Dieterich D T,Han S H,et al.A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: an update[J].Clinical Gastroenterology and Hepatology:the Official Clinical Practice Journal of the American Gastroenterological Association,2006,8(8):1881-1884.
[2] Chen C J,Yang H I,Su J,et al.Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level[J].JAMA:the Journal of the American Medical Association,2006,295(1):65-73.
[3] Liaw Y F,Leung N,Guan R,et al.Asian-pacific consensus statement on the management of chronic hepatitis B:a 2005 update[J].Liver International,2008,2(3):263-283.
[4]王艳玲,张冰,李炳庆.脂肪肝对阿德福韦酯治疗慢性乙型肝炎抗病毒疗效的影响分析[J].重庆医学,2016,45(20):2772-2774.
[5]马玉秀,辛晓恩,于国英.阿德福韦酯抗病毒对慢性乙型肝炎的临床疗效及对外周血T淋巴细胞亚群的影响研究[J].中国生化药物杂志,2014,23(4):88-90.
[6]何麗杰,王静,笪宇蓉.维生素D对慢性乙型肝炎患者免疫功能及抗病毒疗效的影响[J].中国免疫学杂志,2016,32(5):729-733.
[7]盛秋菊,丁洋,窦晓光.恩替卡韦治疗慢性乙型肝炎疗效的早期分层评价[J].实用药物与临床,2010,13(3):167-171.
[8]陈鹏,赵桂鸣,李嘉,等.恩替卡韦治疗慢性乙型肝炎临床评价[J].天津药学,2009,21(4):27-29.
(收稿日期:2016-11-28), http://www.100md.com(曾贵利)
参考文献
[1] Keeffe E B,Dieterich D T,Han S H,et al.A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: an update[J].Clinical Gastroenterology and Hepatology:the Official Clinical Practice Journal of the American Gastroenterological Association,2006,8(8):1881-1884.
[2] Chen C J,Yang H I,Su J,et al.Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level[J].JAMA:the Journal of the American Medical Association,2006,295(1):65-73.
[3] Liaw Y F,Leung N,Guan R,et al.Asian-pacific consensus statement on the management of chronic hepatitis B:a 2005 update[J].Liver International,2008,2(3):263-283.
[4]王艳玲,张冰,李炳庆.脂肪肝对阿德福韦酯治疗慢性乙型肝炎抗病毒疗效的影响分析[J].重庆医学,2016,45(20):2772-2774.
[5]马玉秀,辛晓恩,于国英.阿德福韦酯抗病毒对慢性乙型肝炎的临床疗效及对外周血T淋巴细胞亚群的影响研究[J].中国生化药物杂志,2014,23(4):88-90.
[6]何麗杰,王静,笪宇蓉.维生素D对慢性乙型肝炎患者免疫功能及抗病毒疗效的影响[J].中国免疫学杂志,2016,32(5):729-733.
[7]盛秋菊,丁洋,窦晓光.恩替卡韦治疗慢性乙型肝炎疗效的早期分层评价[J].实用药物与临床,2010,13(3):167-171.
[8]陈鹏,赵桂鸣,李嘉,等.恩替卡韦治疗慢性乙型肝炎临床评价[J].天津药学,2009,21(4):27-29.
(收稿日期:2016-11-28), http://www.100md.com(曾贵利)