门冬氨酸钾镁治疗心力衰竭60例临床效果观察(1)
【摘要】 目的：观察门冬氨酸钾镁治疗心力衰竭的临床效果。方法：将120例心力衰竭患者分为治疗组与对照组，各60例，对照组采用强心、扩张血管、利尿和营养心肌等内科常规治疗，治疗组在此治疗基础上加用门冬氨酸钾镁注射液治疗，1疗程结束后视病情可再行第2疗程治疗。结果：经1疗程治疗后，治疗组症状平均缓解时间、显效率、总有效率优于对照组，差異均有统计学意义(P<0.05)。用药后3～5 d治疗组血清镁和血清钾浓度高于治疗前，差异有统计学意义(P<0.01)。对照组仅血清钾浓度略有升高，但与治疗前比较，差异无统计学意义(P>0.05)。两组治疗后血清镁和血清钾浓度比较，差异有统计学意义(P<0.05)。结论：心衰应用门冬氨酸钾镁治疗方法简单、疗效好、安全性高，值得临床推广应用。
【关键词】 门冬氨酸钾镁； 心力衰竭； 疗效
doi：10.14033/j.cnki.cfmr.2017.24.011 文献标识码 B 文章编号 1674-6805(2017)24-0020-02
, 百拇医药
【Abstract】 Objective：To observe the clinical curative effect of Nmda Potassium Magnesium in the treatment of heart failure.Method：120 patients with heart failure were divided into treatment group and control group(n=60).The control group was given medical conventional treatment，including cardiotonic，dilating blood vessels，diuresis and myocardial nutrition therapy and on the basis of the control group，the treatment group was given Nmda Potassium Magnesium injection，the second course of treatment could be followed depending on the condition after the first course.Result：After one course of treatment，the average alleviate symptoms，significant efficiency and total effective rate of the treatment group were better than those of the control group，the differences were statistically significant(P<0.05).The serum potassium，magnesium concentrations of the treatment group after 3 to 5 days of the treatment were higher than before treatment，the differences were statistically significant(P<0.01).Although serum potassium concentration of the control group after treatment was increased compared with before treatment，the difference was not statistically significant(P>0.05).The differences in the serum potassium，magnesium concentrations between the two groups were statistically significant(P<0.05).Conclusion：The application of Nmda Potassium Magnesium in the treatment of heart failure is simple and has good curative effect，high safety，which is worthy of clinical popularization and application.
, 百拇医药
【Key words】 Nmda potassium magnesium； Heart failure； Curative effect
First-author’s address：Cao County Hospital of Traditional Chinese Medicine，Cao County 274400，China
心力衰竭(以下简称心衰)，是一种由多因引发心肌收缩力减退，心脏前负荷和后负荷过重或异常，引起心功能失代偿，排血量减少无法满足其机体组织代谢需要所产生的一种临床病理生理综合征[1]。治疗心衰长期惯用的利尿剂和洋地黄会导致尿排钾、尿排镁增多，同时伴随患者食物摄入减少、限制盐摄入量、缺氧和继发性醛固酮增多症，均导致缺钾缺镁情况加重[2]。从2014年2月开始，笔者使用门冬氨酸钾镁注射液静滴对60例心衰患者进行治疗，疗效明显，现报道如下。
1 资料与方法
1.1 一般资料
120例患者均为笔者所在医院内科2014年2月-2016年12月收治的心力衰竭患者，全部病例均符合Framingham心力衰竭诊断标准[3]，其中男63例，女57例，年龄13～83岁，平均(47.7±9.8)岁，平均病程(9.0±6.0)年；其中，心肌病5例，心肌炎7例，肺心病27例，冠心病36例，风心病41例，先心病, http://www.100md.com(周勇 袁建喜)
【关键词】 门冬氨酸钾镁； 心力衰竭； 疗效
doi：10.14033/j.cnki.cfmr.2017.24.011 文献标识码 B 文章编号 1674-6805(2017)24-0020-02
, 百拇医药
【Abstract】 Objective：To observe the clinical curative effect of Nmda Potassium Magnesium in the treatment of heart failure.Method：120 patients with heart failure were divided into treatment group and control group(n=60).The control group was given medical conventional treatment，including cardiotonic，dilating blood vessels，diuresis and myocardial nutrition therapy and on the basis of the control group，the treatment group was given Nmda Potassium Magnesium injection，the second course of treatment could be followed depending on the condition after the first course.Result：After one course of treatment，the average alleviate symptoms，significant efficiency and total effective rate of the treatment group were better than those of the control group，the differences were statistically significant(P<0.05).The serum potassium，magnesium concentrations of the treatment group after 3 to 5 days of the treatment were higher than before treatment，the differences were statistically significant(P<0.01).Although serum potassium concentration of the control group after treatment was increased compared with before treatment，the difference was not statistically significant(P>0.05).The differences in the serum potassium，magnesium concentrations between the two groups were statistically significant(P<0.05).Conclusion：The application of Nmda Potassium Magnesium in the treatment of heart failure is simple and has good curative effect，high safety，which is worthy of clinical popularization and application.
, 百拇医药
【Key words】 Nmda potassium magnesium； Heart failure； Curative effect
First-author’s address：Cao County Hospital of Traditional Chinese Medicine，Cao County 274400，China
心力衰竭(以下简称心衰)，是一种由多因引发心肌收缩力减退，心脏前负荷和后负荷过重或异常，引起心功能失代偿，排血量减少无法满足其机体组织代谢需要所产生的一种临床病理生理综合征[1]。治疗心衰长期惯用的利尿剂和洋地黄会导致尿排钾、尿排镁增多，同时伴随患者食物摄入减少、限制盐摄入量、缺氧和继发性醛固酮增多症，均导致缺钾缺镁情况加重[2]。从2014年2月开始，笔者使用门冬氨酸钾镁注射液静滴对60例心衰患者进行治疗，疗效明显，现报道如下。
1 资料与方法
1.1 一般资料
120例患者均为笔者所在医院内科2014年2月-2016年12月收治的心力衰竭患者，全部病例均符合Framingham心力衰竭诊断标准[3]，其中男63例，女57例，年龄13～83岁，平均(47.7±9.8)岁，平均病程(9.0±6.0)年；其中，心肌病5例，心肌炎7例，肺心病27例，冠心病36例，风心病41例，先心病, http://www.100md.com(周勇 袁建喜)