慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者无创呼吸机治疗效果评价(1)
【摘要】 目的：探討慢性阻塞性肺疾病(chronic obstructive pulmonary disease，COPD)合并Ⅱ型呼吸衰竭患者无创呼吸机治疗的价值。
方法：2016年1月-2017年12月收治的110例COPD合并Ⅱ型呼吸衰竭患者，随机分为观察组和对照组，各55例，入院后进行血气分析，对照组采取抗感染、低流量吸氧、呼吸兴奋剂、利痰等措施对症治疗，观察组则在常规治疗的基础上采取无创呼吸机治疗，采取S/T模式，根据患者具体情况调整。结果：治疗3 d，观察组及对照组相关指标均得到改善，且观察组PaO2(70.29±3.65)mm Hg、SpO2(94.26±3.35)%、pH(7.40±0.05)，高于对照组的(63.26±4.22)mm Hg、(90.28±2.28)%、(7.35±0.03)，差异均有统计学意义(P<0.05);呼吸频率(20.05±2.15)次/min、心率(86.38±5.26)次/min、PaCO2(40.26±4.11)mm Hg，低于对照组的(24.03±2.48)次/min、(94.23±5.76)次/min、(45.27±3.90)mm Hg，差异均有统计学意义(P<0.05)，观察组治疗总有效为94.55%，显著高于对照组的81.82%，住院时间(19.35±5.02)d，短于对照组的(24.78±6.13)d，差异均有统计学意义(P<0.05)。
结论：在常规治疗的基础上采用无创呼吸机治疗COPD合并Ⅱ型呼吸衰竭患者，能够改善患者CO2潴留和低氧血症，提高治疗效果，可作为COPD合并Ⅱ型呼吸衰竭患者一项有效治疗方式。
【关键词】 慢性阻塞性肺疾病; Ⅱ型呼吸衰竭; 常规治疗; 无创呼吸机
doi：10.14033/j.cnki.cfmr.2019.02.002 文献标识码 A 文章编号 1674-6805(2019)02-000-03
Efficacy Evaluation of Noninvasive Ventilation in Patients with Chronic Obstructive Pulmonary Disease Combined with Type Ⅱ Respiratory Failure/LIU Jiayun.//Chinese and Foreign Medical Research，2019，17(2)：-5
【Abstract】 Objective：To explore the value of non-invasive ventilator therapy in patients with chronic obstructive pulmonary disease(COPD)type Ⅱ respiratory failure.Method：From January 2016 to December 2017，110 patients with COPD Ⅱ respiratory failure admitted were randomly divided into the observation group and the control group，55 cases in each group.Blood gas analysis was carried out after admission.The control group received symptomatic treatment such as anti-inflammatory，low flow oxygen inhalation，respiratory stimulant and expectoration.The observation group was treated with noninvasive ventilator on the basis of conventional treatment.Take the S/T mode，according to the specific situation of the patient.Result：Three days later，the related indexes of the observation group and the control group were improved.The observation group PaO2 (70.29±3.65)mm Hg，SpO2 (94.26±3.35)%，pH (7.40±0.05)，were higher than (63.26±4.22)mm Hg，(90.28±2.28)% and (7.35±0.03) of the control group.The differences were statistically significant(P<0.05).Respiratory frequency (20.05±2.15)times/min，heart rate (86.38±5.26)times/min，PaCO2 (40.26±4.11)mm Hg，were lower than (24.03±2.48)times/min，(94.23±5.76)times/min and (45.27±3.90)mm Hg of the control group，the differences were statistically significant(P<0.05).The total effective rate of the observation group was 94.55%，which was higher than that of the control group(81.82%).The duration of stay (19.35±5.02)d，was lower than (24.78±6.13)d of the control group.The differences were statistically significant(P<0.05).Conclusion：On the basis of routine treatment with noninvasive ventilation in the treatment of COPD patients with type Ⅱ respiratory failure，and can improve the retention of CO2 and hypoxemia，improve the therapeutic effect，can be used as a effective treatment in patients with COPD type Ⅱ respiratory failure., http://www.100md.com(刘加云)
方法：2016年1月-2017年12月收治的110例COPD合并Ⅱ型呼吸衰竭患者，随机分为观察组和对照组，各55例，入院后进行血气分析，对照组采取抗感染、低流量吸氧、呼吸兴奋剂、利痰等措施对症治疗，观察组则在常规治疗的基础上采取无创呼吸机治疗，采取S/T模式，根据患者具体情况调整。结果：治疗3 d，观察组及对照组相关指标均得到改善，且观察组PaO2(70.29±3.65)mm Hg、SpO2(94.26±3.35)%、pH(7.40±0.05)，高于对照组的(63.26±4.22)mm Hg、(90.28±2.28)%、(7.35±0.03)，差异均有统计学意义(P<0.05);呼吸频率(20.05±2.15)次/min、心率(86.38±5.26)次/min、PaCO2(40.26±4.11)mm Hg，低于对照组的(24.03±2.48)次/min、(94.23±5.76)次/min、(45.27±3.90)mm Hg，差异均有统计学意义(P<0.05)，观察组治疗总有效为94.55%，显著高于对照组的81.82%，住院时间(19.35±5.02)d，短于对照组的(24.78±6.13)d，差异均有统计学意义(P<0.05)。
结论：在常规治疗的基础上采用无创呼吸机治疗COPD合并Ⅱ型呼吸衰竭患者，能够改善患者CO2潴留和低氧血症，提高治疗效果，可作为COPD合并Ⅱ型呼吸衰竭患者一项有效治疗方式。
【关键词】 慢性阻塞性肺疾病; Ⅱ型呼吸衰竭; 常规治疗; 无创呼吸机
doi：10.14033/j.cnki.cfmr.2019.02.002 文献标识码 A 文章编号 1674-6805(2019)02-000-03
Efficacy Evaluation of Noninvasive Ventilation in Patients with Chronic Obstructive Pulmonary Disease Combined with Type Ⅱ Respiratory Failure/LIU Jiayun.//Chinese and Foreign Medical Research，2019，17(2)：-5
【Abstract】 Objective：To explore the value of non-invasive ventilator therapy in patients with chronic obstructive pulmonary disease(COPD)type Ⅱ respiratory failure.Method：From January 2016 to December 2017，110 patients with COPD Ⅱ respiratory failure admitted were randomly divided into the observation group and the control group，55 cases in each group.Blood gas analysis was carried out after admission.The control group received symptomatic treatment such as anti-inflammatory，low flow oxygen inhalation，respiratory stimulant and expectoration.The observation group was treated with noninvasive ventilator on the basis of conventional treatment.Take the S/T mode，according to the specific situation of the patient.Result：Three days later，the related indexes of the observation group and the control group were improved.The observation group PaO2 (70.29±3.65)mm Hg，SpO2 (94.26±3.35)%，pH (7.40±0.05)，were higher than (63.26±4.22)mm Hg，(90.28±2.28)% and (7.35±0.03) of the control group.The differences were statistically significant(P<0.05).Respiratory frequency (20.05±2.15)times/min，heart rate (86.38±5.26)times/min，PaCO2 (40.26±4.11)mm Hg，were lower than (24.03±2.48)times/min，(94.23±5.76)times/min and (45.27±3.90)mm Hg of the control group，the differences were statistically significant(P<0.05).The total effective rate of the observation group was 94.55%，which was higher than that of the control group(81.82%).The duration of stay (19.35±5.02)d，was lower than (24.78±6.13)d of the control group.The differences were statistically significant(P<0.05).Conclusion：On the basis of routine treatment with noninvasive ventilation in the treatment of COPD patients with type Ⅱ respiratory failure，and can improve the retention of CO2 and hypoxemia，improve the therapeutic effect，can be used as a effective treatment in patients with COPD type Ⅱ respiratory failure., http://www.100md.com(刘加云)