【摘要】 目的：探讨乌司他丁早期使用对产后失血性休克患者肾脏及炎症指标的影响。方法：选取2015-2018年在笔者所在医院ICU住院诊断产后失血性休克患者67例，随机分为观察组35例和对照组32例。对照组采用常规治疗原发病、输血、补液、升血压药物等处理，观察组在对照组基础上加用乌司他丁。比较两组患者治疗3 d后BUN、Cr、IL-6、TNF-α等指标，急性肾损伤例数。结果：观察组患者急性肾损伤例数较对照组减少(P<0.05);观察组BUN、Cr、IL-6、TNF-α水平较对照组低(P<0.05)。结论：早期使用乌司他丁治疗产后失血性休克患者有助于减轻肾脏损伤和降低炎症指标。

    【关键词】 乌司他丁; 休克; 产后出血; 肾保护

    doi：10.14033/j.cnki.cfmr.2019.15.017 文献标识码 B 文章编号 1674-6805(2019)15-00-02

    【Abstract】 Objective：To investigate the effects of early use of Ulinastatin on renal and inflammatory markers in patients with postpartum hemorrhagic shock.Method：67 patients with postpartum hemorrhagic shock diagnosed in our hospital in ICU from 2015 to 2018 were selected.The patients were randomly divided into observation group(35 cases) and control group(32 cases).The control group was treated with conventional treatment of primary disease ......