米曲菌胰酶片联合莫沙必利治疗胃大部切除术后消化不良的临床观察(1)
【摘要】 目的：觀察米曲菌胰酶片联合莫沙必利治疗胃大部切除术后消化不良的效果。方法：随机选取2017年2月-2018年8月笔者所在医院胃大部切除术后消化不良患者80例，分为治疗组和对照组，各40例。治疗组口服米曲菌胰酶片和莫沙必利进行治疗，对照组口服莫沙必利进行治疗，疗程2周。观察比较两组患者在治疗1、2周消化不良症状的改善情况、两组患者治疗2周后的效果及汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)评分等。结果：治疗2周后，治疗组不良症状评分为(11.26±1.43)分，对照组为(17.36±2.37)分，治疗组不良症状评分明显优于对照组，差异有统计学意义(P<0.05)。治疗组总有效率为90.0%，对照组为70.0%，治疗组总有效率明显高于对照组，差异有统计学意义(P<0.05)。治疗组HAMA、HAMD评分分别为(12.27±3.46)、(12.48±2.66)分，低于对照组的(17.74±3.04)、(19.99±3.08)分，差异均有统计学意义(P<0.05)。结论：米曲菌胰酶片联合莫沙必利有助于治疗胃大部切除术后的消化不良，临床效果良好，建议采用。
【关键词】 米曲菌胰酶片; 莫沙必利; 胃大部切除术; 消化不良
doi：10.14033/j.cnki.cfmr.2019.25.005 文献标识码 A 文章编号 1674-6805(2019)25-00-03
Efficacy of Oryz-aspergillus Enzyme and Pancreatin Tablets Combined with Mosapride in the Treatment of Dyspepsia in Patients after Subtotal Gastrectomy/GUO Chaoshu，HUANG Zhonghua，LI Suping，et al.//Chinese and Foreign Medical Research，2019，17(25)：-14
【Abstract】 Objective：To investigate the efficacy of Oryz-aspergillus Enzyme and Pancreatin Tablets combined with Mosapride in the treatment of dyspepsia in patients after subtotal gastrectomy.Method：Eighty cases of dyspepsia after subtotal gastrectomy were randomly selected and divided into treatment group(n=40) and control group(n=40).The treatment group was treated by Oryz-aspergillus Enzyme and Pancreatin Tablets combined with Mosapride，while the control group was treated by oral Mosapride for 2 weeks.The improvement of dyspepsia symptoms in 1 and 2 weeks of treatment，the efficacy of the two groups after treatment，the scores of Hamilton anxiety scale(HAMA) and Hamilton depression scale(HAMD) were observed and compared.Result：After treatment of 2 weeks，the score of adverse symptoms in the treatment group was (11.26±1.43)points and which in the control group was (17.36±2.37)points.The score of adverse symptoms in the treatment group was significantly better than that in the control group，the differences was statistically significant(P<0.05).The total effective rate was 90.0% in the treatment group and 70.0% in the control group.The total effective rate in the treatment group was significantly higher than that in the control group，the differences was statistically significant(P<0.05).The scores of HAMA and HAMD in the treatment group were (12.27±3.46)points，(12.48±2.66)points respectively，lower than (17.74±3.04)points，(19.99±3.08)points in the control group，the differences were statistically significant(P<0.05).Conclusion：Oryz-aspergillus Enzyme and Pancreatin Tablets combined with Mosapride is helpful in the treatment of dyspepsia after subtotal gastrectomy，and the clinical effect is good.It is recommended to adopt it., 百拇医药(郭朝书 黄中华 李素萍 陈明)
【关键词】 米曲菌胰酶片; 莫沙必利; 胃大部切除术; 消化不良
doi：10.14033/j.cnki.cfmr.2019.25.005 文献标识码 A 文章编号 1674-6805(2019)25-00-03
Efficacy of Oryz-aspergillus Enzyme and Pancreatin Tablets Combined with Mosapride in the Treatment of Dyspepsia in Patients after Subtotal Gastrectomy/GUO Chaoshu，HUANG Zhonghua，LI Suping，et al.//Chinese and Foreign Medical Research，2019，17(25)：-14
【Abstract】 Objective：To investigate the efficacy of Oryz-aspergillus Enzyme and Pancreatin Tablets combined with Mosapride in the treatment of dyspepsia in patients after subtotal gastrectomy.Method：Eighty cases of dyspepsia after subtotal gastrectomy were randomly selected and divided into treatment group(n=40) and control group(n=40).The treatment group was treated by Oryz-aspergillus Enzyme and Pancreatin Tablets combined with Mosapride，while the control group was treated by oral Mosapride for 2 weeks.The improvement of dyspepsia symptoms in 1 and 2 weeks of treatment，the efficacy of the two groups after treatment，the scores of Hamilton anxiety scale(HAMA) and Hamilton depression scale(HAMD) were observed and compared.Result：After treatment of 2 weeks，the score of adverse symptoms in the treatment group was (11.26±1.43)points and which in the control group was (17.36±2.37)points.The score of adverse symptoms in the treatment group was significantly better than that in the control group，the differences was statistically significant(P<0.05).The total effective rate was 90.0% in the treatment group and 70.0% in the control group.The total effective rate in the treatment group was significantly higher than that in the control group，the differences was statistically significant(P<0.05).The scores of HAMA and HAMD in the treatment group were (12.27±3.46)points，(12.48±2.66)points respectively，lower than (17.74±3.04)points，(19.99±3.08)points in the control group，the differences were statistically significant(P<0.05).Conclusion：Oryz-aspergillus Enzyme and Pancreatin Tablets combined with Mosapride is helpful in the treatment of dyspepsia after subtotal gastrectomy，and the clinical effect is good.It is recommended to adopt it., 百拇医药(郭朝书 黄中华 李素萍 陈明)
参见：首页 > 医疗版 > 疾病专题 > 小儿科 > 消化系统和营养障碍性疾病 > 消化不良