帕利哌酮缓释片与利培酮片治疗精神分裂症对照研究(2)
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综上所述,帕利哌酮缓释片与利培酮治疗精神分裂症均效果满意,但帕利哌酮缓释片的药物不良反应少于利培酮,且不影响催乳素水平,是一种有效、安全的一线抗精神病药物,值得临床推广应用。
参考文献
[1]Dremencov E,MansaniMEI, Blier P, et al. Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norep inephrine neurons[J]. Psychopharmacology, 2007, 194: 63272
[2]Aravagin M,Marder SR. Brain, plasma and tissue pharmacokinetics of risperidone and hydroxyl risperidone after separate oral administration to rats[J]. Psychopharmacology ......
综上所述,帕利哌酮缓释片与利培酮治疗精神分裂症均效果满意,但帕利哌酮缓释片的药物不良反应少于利培酮,且不影响催乳素水平,是一种有效、安全的一线抗精神病药物,值得临床推广应用。
参考文献
[1]Dremencov E,MansaniMEI, Blier P, et al. Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norep inephrine neurons[J]. Psychopharmacology, 2007, 194: 63272
[2]Aravagin M,Marder SR. Brain, plasma and tissue pharmacokinetics of risperidone and hydroxyl risperidone after separate oral administration to rats[J]. Psychopharmacology ......
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