支原体感染与宫外孕的关系(2)
3.2 沙眼衣原体及解脲支原体的防治:1)对高危人群进行CT、UU检测,如宫颈病变、多个性伴侣者、有盆腔炎病史者,国外研究[5]发现行大规模的额人群普查和疫苗的研制也很重要;2)检测阳性者,行药敏试验,用敏感药物,疗程2周,与性伴侣同时用药,减少反复感染机会,3) CT、UU阳性者尽量避免做宫腔操作,如人工流产、去放宫内节育器、输卵管造影,减少医源性的上行性感染;4)因慢性盆腔炎的CT、UU感染一般不单独存在,且易反复发作,故药物治疗同时,亦可行中药活血化瘀保留灌肠,提高临床治疗效果,改善患者的生活质量,是现代临床的治疗理念。
3.3 综上所述,早发现CT、UU感染,并及时治疗,可以减少其上行感染宫腔、盆腔,减少CT、UU感染所致的盆腔炎、输卵管所致的不孕症;治疗CT阳性的反复发作的慢性盆腔炎中,可以减少其发作频率,减少盆腔疼痛,提高患者的生活质量。
参考文献
[1] 薛凤霞,妇产科学,生殖道衣原体感染
[2] 张帝开,贾继辉,邝健全,等。解脲支原体对兔输卵管粘膜上皮细胞致病性研究[J].中国微生态杂志,2003.15(6)
[3] Machado AC, Guimares EM, Sakurai E,et al, High titers of Chlamydia trachomatis antibodies in Brazilian women with tubal occlusion or previous ectopic pregnancy. Infect Dis Obstet Gynecol. 2007;2007:24816
[4] Shao R, Zhang SX, Weijdegrd B,et al. Nitric oxide synthases and tubal ectopic pregnancies induced by Chlamydia infection: basic and clinical insights. Mol Hum Reprod. 2010 Dec;16(12):907-15
[5] Brandie D Taylor and Catherine L Haggerty. Management of Chlamydia trachomatis genital tract infection: screening and treatment challenges. Infect Drug Resist. 2011; 4: 19-29, http://www.100md.com(杜筛萍,瞿玉侠)
3.3 综上所述,早发现CT、UU感染,并及时治疗,可以减少其上行感染宫腔、盆腔,减少CT、UU感染所致的盆腔炎、输卵管所致的不孕症;治疗CT阳性的反复发作的慢性盆腔炎中,可以减少其发作频率,减少盆腔疼痛,提高患者的生活质量。
参考文献
[1] 薛凤霞,妇产科学,生殖道衣原体感染
[2] 张帝开,贾继辉,邝健全,等。解脲支原体对兔输卵管粘膜上皮细胞致病性研究[J].中国微生态杂志,2003.15(6)
[3] Machado AC, Guimares EM, Sakurai E,et al, High titers of Chlamydia trachomatis antibodies in Brazilian women with tubal occlusion or previous ectopic pregnancy. Infect Dis Obstet Gynecol. 2007;2007:24816
[4] Shao R, Zhang SX, Weijdegrd B,et al. Nitric oxide synthases and tubal ectopic pregnancies induced by Chlamydia infection: basic and clinical insights. Mol Hum Reprod. 2010 Dec;16(12):907-15
[5] Brandie D Taylor and Catherine L Haggerty. Management of Chlamydia trachomatis genital tract infection: screening and treatment challenges. Infect Drug Resist. 2011; 4: 19-29, http://www.100md.com(杜筛萍,瞿玉侠)