二氢杨梅素抗肿瘤最新研究进展(1)
摘 要: 二氢杨梅素是黄酮类化合物之一,大量存在于藤茶植物中。研究表明二氢杨梅素具有抗肿瘤、清除自由基、抗氧化、抗血栓和消炎等多种功效[1-3]。本文主要综述二氢杨梅素抗肿瘤活性和5种抗肿瘤作用机制:诱导肿瘤细胞凋亡;诱导肿瘤细胞自噬;抑制肿瘤细胞侵袭、转移;抑制肿瘤血管形成以及细胞周期阻滞。二氢杨梅素在体外和体内抗肿瘤方面效果明显,其对抗肿瘤药物的研究具有重要意义。关键词:二氢杨梅素;肿瘤;自噬。
Abstract: Dihydromyricetin is one of the flavonoids, abounding in rattan tea plants. Studies have shown that dihydromyricetin has anti-tumor, scavenging free radicals, antioxidation, antithrombotic and anti-inflammatory effect[1-3]. This article mainly reviews dihydromyricetin antitumor activity and 5 kinds of antitumor mechanisms: The function of inducing tumor cell apoptosis ......
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