摘要：目的：对比腹腔镜与小切口开腹修补术治疗急性胃十二指肠溃疡穿孔的临床疗效。方法：选取2014年1月至2015年1月我院收治的95例急性胃十二指肠溃疡穿孔患者为研究对象，根据手术方式将患者分为腹腔镜组(49例)和开腹组(46例)，腹腔镜组行腹腔镜修补术，开腹组行小切口开腹修补术。对比两组的治疗总有效率、死亡率、术中和术后情况。结果：腹腔镜组的总有效率(59.18%)高于开腹组(26.09%)，死亡率(30.61%)低于开腹组(52.17%)；手术时间、术中出血量、术后排气时间以及术后使用镇痛药人数均少于开腹组；腹腔镜组患者术后并发症发生率(8.16%)低于开腹组(23.91%)，差异均具有统计学意义(P<0.05)。结论：腹腔镜修补术治疗急性胃十二指肠溃疡穿孔疗效优于开腹手术，值得在临床上推广。

    关键词：急性胃十二指肠溃疡穿孔；腹腔镜修补术；小切口开腹修补术

    Abstract：Objective： To compare the efficacy of laparoscopic and small incision laparotomy repair in the acute gastro duodenal ulcer perforation Methods： 95 cases of acute gastro duodenal ulcer perforation patients were included the study from January 2014 to January 2015 in our hospital. According to the different surgical methods the case were divided into laparoscopic group (49 cases) and laparotomy group (46 cases).Laparoscopic group used laparoscopic repair ......