胸水癌胚抗原诊断恶性胸腔积液的价值(1)
摘要: 目的: 探讨胸水癌胚抗原(CEA)诊断恶性胸腔积液的价值。方法: 回顾性分析2010年1月-2015年1月收住我院呼吸科的胸腔积液患者108例,采用酶免疫分析法(EIA)测胸水CEA水平,分为恶性胸腔积液和非恶性胸腔积液,作ROC曲线,运用最大约登指数法确定CEA诊断恶性胸腔积液的最佳临界值及相应的灵敏度(SEN)和特异度(SPE)。结果: 恶性胸腔积液患者胸水CEA水平显著高于非恶性胸腔积液患者(P<0.05)。CEA诊断恶性胸腔积液的ROC曲线下面积(AUC)是0.79,最佳临界值是7.8ng/ml,对应的SEN和SPE分别是0.71和0.84。结论: CEA在诊断恶性胸腔积液中具有较高价值。关键词: 癌胚抗原;恶性胸腔积液;诊断;
Abstract:Objective To explore the role of carcinoembryonic antigen (CEA) in diagnosis of malignant pleural effusions. Methods 108 patients with pleural effusions were included. CEA levels in pleural effusions were detected by EIA and the pleural effusions were divided into malignant and non- malignant. SPSS17.0 was used to make ROC ......
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