摘要：线粒体作为主要的供能细胞器，亦是高等动物细胞核外仅有DNA的微结构。由于线粒体基因结构及功能特性，决定其易损伤和突变的特点，在肿瘤发生发展过程中亦起重要作用，国内外的大量研究已予以证明。近年来，也有学者研究其基因改变与喉癌癌变的相关性，本文就线粒体基因改变在喉癌癌变中的作用加以综述。

    关键词：线粒体基因改变；喉癌癌变；肿瘤

    Abstract： Mitochondria，the higher animals outside the nucleus contains organelles containing DNA，that Its main role provide energy for the cell.A large number of domestic and foreign research have proved that Because the structure and functional properties of mitochondrial genes，causing it easy to damage and mutation，which also play an Important role in tumorigenesis.In recent years ......