孙爱红 王方方 管俊 谢晓艳 马莉

    摘要：目的：回顾分析二例诊断为再障患者，半年后复查骨髓已为急性白血病(M2)，分析其转变的可能原因。方法：回顾分析二例患者初诊时资料，如基本临床资料，血常规中红细胞参数，如红细胞平均体积、平均血红蛋白量，及多部位骨髓涂片特点；进一步分析治疗方法，尤其强化免疫抑制治疗对转化的影响。结果：二例患者因贫血就诊，初诊时经过骨髓涂片、活检诊断为再障，一例仅给予安雄及再造生血片促造血治疗，另一例强化免疫抑制治疗效果不明显，两例患者均在半年后复查骨髓诊断为急性白血病。

    关键词：再障、急性白血病、转变、强化免疫治疗

    Abstract：Purpose ： Two cases diagnosed as aplastic anemia ， who were diagnosed as acute leukemia (M2) six months after one patient had received promoting hematoietic activity and another patient had received intensive immunosuppressive therapy including ATG and cisclosporine(CsA)， were retrospectively analyzed. Methods ： They was retrospectively analysed about her basic information such as clinical data ......