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编号:12811330
术后高热病人氧化应激状态观察(1)
http://www.100md.com 2014年6月5日 施伟民 庄志祥
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     摘要:目的:研究外科术后高热与氧化应激的关联性,为外科术后发热治疗寻找新的思路。方法:研究2012 -08?2013-09本院外科34例住院病人,术后检测血清丙二醛浓度变化,比较术后高热组和非高热组病人在术后第2d,4d的MDA浓度差异,同时记录出器官功能障碍的数目,分析MDA浓度与器官功能障碍的关系。结果: 术后高热组病人MDA浓度高于非高热组(11.79± 1.92)μmol/Lvs(7.21 ±1.79)μmol/L,P<0.01,MDA浓度与器官功能障碍数目相关。r =0.830,P <0.01)。结论:术后高热患者体内存在严重氧化应激而导致病人器官功能损害。

    关键词:手术;发热;氧化应激

    Clinical Analysis Oxidative Stress in Fever - patients after Operation SHI Weimin/SHI Wei – min,ZHUANG Zhi -xiang// Department of General surgency, The AffiliatedSuzhou TCM Hospital of Nanjing Chinese Medicine Uiversity,Suzhou 215003, China

    Abstract:Objective :Toinvestigate the oxidative stress in postoperative fever -patientsandexploreanew strategy for it. Methods :34 postoperative patients divided into fever - group and non - fever - group were involved. Serum malondialdehyde (MDA); data of were mesured,at the second and :the fourth day after operation. MDA level were comparedbetween,different groups. At the same lime organ function was observed and the numbers of dysfunction organ were recorded ......

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