【摘要】目的 研究牡丹皮的化学成分。方法 利用反相色谱的方法分离纯化, 根据化合物的化学性质与光谱数据鉴定结构。结果 牡丹皮的70%乙醇提取物中分得8个化合物, 确定其结构分别为mudanpioside-E (1), oxypaeoniflorin (2)，mudanpioside A (3), 尿嘧啶核甙 (4)，胸腺嘧啶脱氧核苷 (5)，丹皮酚(6), 色氨酸 (7)，没食子酸 (8)。结论 化合物4和5为首次从该植物中分得。

    【关键词】牡丹皮；水溶性成分

    Studies on Chemical Constituents in the Root cortex of Paeonia Suffruticosa YU Zhao-Hai.(Department of Pharmacy, People's Hospital of Jiaonan, Jiaonan 266400, Shandong, China)

    【Abstract】Objective To study the chemical constituents from Paeonia suffruticosa.Methods The constituents were isolated by reverse-phased materials, and their structures were characterized by chemical property and spectral analysis.Results Eight compounds were isolated from the 70% ethanol extract of the leaves of Paeonia suffruticosa. Their structures were elucidated as mudanpioside-E (1), oxypaeoniflorin (2), mudanpioside A (3), uridine (4), thymidine (5), paeonol (6) tryptophan (7) and gallic acid (8), respectively. Conclusion Compounds 4 and 5 are isolated from this plant for the first time. ......