桑银降糖活性成分对大鼠胰腺细胞凋亡相关蛋白bck-2和bax表达的影响(3)
参考文献
[1] W.L. Li,H.C.Zheng, J.Bukuru,et al. Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. Journal of Ethnopharmacology, 2004, 92:1-21.
[2]赵骏,高岚.桑叶多糖的降糖降脂作用.天津中医药.2004,21: 505-506.
[3] Lupi R, Dotta F, Marsella L,et al.Prolonged exposure to freefatty acids has cytostatic and pro-apoptotic effects on humanpancreatic islets: evidence that beta-cell death is caspase me-diated , partially dependent on ceramide pathway and Bcl-2redulated. Diabetes,2002,51:1437-1442.
[4] Piro S, Anello M, Di Pietro C,et al.Chronic exposure to freefatty acids or high glucose induces apoptosis in rat pancreaticislets: possible role of oxidative stress.Metabolism, 2002, 51:1340-1347.
[5]NandhiniAT，ThirunavukkarasuV，AnuradhaCV.Stimulation ofGlucoseUtilization and inhibition of protein glycation andAGE productsby taurine[J].Acta PhysiolScnad，2004，181(3)：297-303.
[6] 余华荣、张能、董毅龙等，牛磺酸对STZ诱导大鼠胰岛细胞凋亡及BCL-xL和BAX表达变化的影响。基础医学与临床2006；26(6)：613～616.
[7] Cheng EH,Kirsch DG, Clen RJ,et al·Conversion of Bcl-2 to a Baxlikedeath effector by caspases〔J〕·Science, 1997; 278: 1966-8.
[8] Reed JC·Bcl-2 and the regulation of programmed cell death〔J〕·J Cell Bio,l 1994; 124: 1-6·
[9] Heermeier K, Benedict M, Li M,et al.Bax and Bcl-xS areinduced at the onset of apoptosis in involuting mammary ep-ithelial cells. Mech Dev,1996,56:197-207
[10] 宋福印，栗德林，周景华等，消渴停对胰岛B细胞凋亡及相关基因Bcl-2、Fas蛋白表达的影响. 中国中医药信息杂志2001；8(6)：24～26.
[11]Federici M, Hribal M, Perego L,et al.High glucose causesapoptosis in cultured human pancreatic islets of Langerhans: apotential role for regulation of specific Bcl family genes towardan apoptotic cell death program.Diabetes,2001,50(6):1290-1301.
[12] Thomas D, Yang H, Boffa DJ,et al.Proapoptotic bax is hyperexpressed in isolated human islets compared with antiapoptotic Bcl-2. Transplantation,2002,74:1489-1496.
*本课题由山东省科技厅资助，科技攻关项目，编号(2005GG3202043)。
作者简介：
唐天华研究员 ，山东省医学科学院基础医学研究所。, http://www.100md.com(唐天华 李春林 任 霞 任海全 张之勇 姜国胜)
[1] W.L. Li,H.C.Zheng, J.Bukuru,et al. Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. Journal of Ethnopharmacology, 2004, 92:1-21.
[2]赵骏,高岚.桑叶多糖的降糖降脂作用.天津中医药.2004,21: 505-506.
[3] Lupi R, Dotta F, Marsella L,et al.Prolonged exposure to freefatty acids has cytostatic and pro-apoptotic effects on humanpancreatic islets: evidence that beta-cell death is caspase me-diated , partially dependent on ceramide pathway and Bcl-2redulated. Diabetes,2002,51:1437-1442.
[4] Piro S, Anello M, Di Pietro C,et al.Chronic exposure to freefatty acids or high glucose induces apoptosis in rat pancreaticislets: possible role of oxidative stress.Metabolism, 2002, 51:1340-1347.
[5]NandhiniAT，ThirunavukkarasuV，AnuradhaCV.Stimulation ofGlucoseUtilization and inhibition of protein glycation andAGE productsby taurine[J].Acta PhysiolScnad，2004，181(3)：297-303.
[6] 余华荣、张能、董毅龙等，牛磺酸对STZ诱导大鼠胰岛细胞凋亡及BCL-xL和BAX表达变化的影响。基础医学与临床2006；26(6)：613～616.
[7] Cheng EH,Kirsch DG, Clen RJ,et al·Conversion of Bcl-2 to a Baxlikedeath effector by caspases〔J〕·Science, 1997; 278: 1966-8.
[8] Reed JC·Bcl-2 and the regulation of programmed cell death〔J〕·J Cell Bio,l 1994; 124: 1-6·
[9] Heermeier K, Benedict M, Li M,et al.Bax and Bcl-xS areinduced at the onset of apoptosis in involuting mammary ep-ithelial cells. Mech Dev,1996,56:197-207
[10] 宋福印，栗德林，周景华等，消渴停对胰岛B细胞凋亡及相关基因Bcl-2、Fas蛋白表达的影响. 中国中医药信息杂志2001；8(6)：24～26.
[11]Federici M, Hribal M, Perego L,et al.High glucose causesapoptosis in cultured human pancreatic islets of Langerhans: apotential role for regulation of specific Bcl family genes towardan apoptotic cell death program.Diabetes,2001,50(6):1290-1301.
[12] Thomas D, Yang H, Boffa DJ,et al.Proapoptotic bax is hyperexpressed in isolated human islets compared with antiapoptotic Bcl-2. Transplantation,2002,74:1489-1496.
*本课题由山东省科技厅资助，科技攻关项目，编号(2005GG3202043)。
作者简介：
唐天华研究员 ，山东省医学科学院基础医学研究所。, http://www.100md.com(唐天华 李春林 任 霞 任海全 张之勇 姜国胜)