摘 要目的:评价宫腔镜直视下输卵管插管注入甲氨蝶呤(MTX)治疗输卵管妊娠的临床效果。方法:选取输卵管妊娠的患者38例,随机分为两组,试验组23例,采用宫腔镜直视下输卵管插管一次性注射MTX 40mg治疗;对照组15例,采用一次性肌肉注射MTX 50mg/m2治疗。结果:试验组较对照组血β-HCG下降快,转阴时间短,不良反应少,差异有显著性(P<0.05),但成功率差异无显著性。结论:宫腔镜直视下输卵管内注入MTX治疗早期输卵管妊娠的临床效果明显优于肌肉注射术。

    关键词输卵管妊娠;宫腔镜;甲氨蝶呤;疗效

    AbstractObjective:To evaluate clinical effects of treating tubal pregancy by tubal catheterization and injecting amethopterin (MTX) by hysteroscopy.Methods:38 women of tubal pregancy were divided into two groups randomly.23 women wereunderwent tubal catheterization and injected MTX 40mg by hysteroscopy as trial group.15 women were treated by injecting in muscle MTX 50mg/m2 as control group.Results:β-HCG decreased more quickly,negtive time of β-HCG was obviosly shorter and side effects of MTX was rare in trial group than that in control group (P<0.05).But there was no significant differences in treating rate of success.Conclusion: Therapeutic effects of tubal catheterization and injecting MTX by hysteroscopy is obviously better than that by muscle. ......