摘要目的：分析探讨左氧氟沙星不良反应特点，为临床合理用药提供参考。方法：采用回顾性分析方法对2006～2007年泰安市药品不良反应监测中心收到的134例左氧氟沙星不良反应病例报告进行统计分析。结果：左氧氟沙星所致不良反应共累及10个系统—器官，其中皮肤及附件损害最多，占41.04%；其次为消化系统损害，占30.63%。结论：左氧氟沙星所致不良反应可累及全身各个系统，临床上应慎重使用。

    关键词左氧氟沙星；不良反应；病例分析

    AbstractObjective:Analyzed adverse drug reaction(ADR)of Levofloxacin to provide the references information for rational drug in clinical practice. Methods:134 ADR reports of Levofloxacin collected by Taian Center for ADR Monitoring from 2006 to2007were analyzed using retrospective study method. Results:The adverse effects involved 10 systems or organs with the most frequent in skin and its appendages(41.04%),followed by damages in gastrointestinal tract(30.63%). Conclusion: Levofloxacin could cause multi-system and multi-organ ADR with wide variety of clinical manifestations.Attention should be paid to ADR of Levofloxacin to ensure safe and rational drug use.

    Key words Levofloxacin;adverse drug reaction;analysis

    中图分类号：994.11文献标识码：A

    为了给临床合理用药和护理工作提供更详实的参考 ......