摘 要目的：观察急性胰腺炎早期对肾脏的影响。方法：用生化、免疫方法检测43例急性胰腺炎(急性坏死型28例，水肿型15例)患者发病及预后血、尿淀粉酶(AMY)、尿微量白蛋白(ALB)、转铁蛋白(TRF)、α1-微球蛋白(α1-MG)、β2-微球蛋白(β2-MG)、免疫球蛋白G(IgG)。结果：血AMY、尿α1-MG、β2-MG在治疗前和治疗后有非常显著的统计学差异(P<0.01)，尿ALB、TRF、IgG差异不显著(P>0.05)。结论：急性胰腺炎早期对肾小管会造成损害，对肾小球损害不明显。

    关键词急性胰腺炎；肾损害；淀粉酶

    AbstractObjective：To observe the damage of kidney in early pertod of acute pancreatitis. Methods：Serum AMYand urine AMY ALB TRF α1-MG β2-MG IgG were detected with biochemical assay and immunoassay. Results：The results of serum AMY and urine α1-MG、β2-MG were lower after treatment (P<0.01),but urine AJB TRF IgG had nodifference (P>0.05). Conclusion：Early acute pancreatitis can damage renal tubule,butacinus renis has no damage.

    Key words Acute pancreatitis；damage of renal；AMY

    急性胰腺炎(acute pancreatitis)是多种病因导致胰酶在胰腺内被激活后引起胰腺组织自身消化、水肿、出血甚至坏死的炎症反应 ......