摘 要目的:观察盐酸丁咯地尔、依达拉奉联合治疗急性脑梗死的疗效。方法:选择我院2007.8至2008.10临床确诊脑梗死的病人87例,随机分为2组,盐酸丁咯地尔、依达拉奉(治疗组)42例,胞二磷胆碱、复方丹参(对照组)45例,疗程均为14天观察治疗后的神经功能改善情况及血液流变学的变化。结果:治疗组总有效率85.7%,对照组66.6%,2组总有效率比较χ2=4.304,P<0.05,治疗组疗效明显优于对照组,且无明显副作用。结论:盐酸丁咯地尔、依达拉奉联合治疗急性脑梗死能显著提高脑梗死患者的疗效,且无明显不良反应。

    关键词盐酸丁咯地尔;依达拉奉;急性脑梗死

    AbstractObjective:To investigate the therapeutic effect of Buflomedil and Edaravone used on combination on acute cerebral infarction (ACI).Methods: 87patients with acute cerebral infarction were chosen in our hospital from 2007.8-2008.10, and were divided into 2 groups in randomly .42 cases (experiment group ) were treated by Buflomedil and Edaravone, and 45 cases (control group) were treated bycytidini diphosphatis choline and citicoline , The period of treatment was 14 days.Results:The effective rate is 85.7% in experiment group, and 66.6% in control group. The total effective rate of treatment group higher than control group obviouslyχ2=4.304 p<0.05 No significant side-effect was observed. Conclusion :Buflomedil and Edarauone treatment has effect on reducing the disabled rate and enhancing the life qualiy in patients with ACI. ......