【摘要】目的：探讨心理干预对慢性乙型肝炎患者抗病毒治疗期间肝功能及病情的影响。方法：心理干预组59例，在常规抗病毒药物治疗的基础上进行心理干预，对照组49例单纯进行常规抗病毒药物治疗，在干预前后分别检测肝功能及乙肝表面抗原(HBsAg)，比较两次检测的结果，以观察心理干预在抗病毒治疗期间的作用。结果：心理干预前两组患者肝功能、HBsAg无差别，干预后两组患者ALT，AST，ALB，HBsAg转阴率差别有显著意义(P<0.05)。结论：在常规药物治疗基础上配合心理干预，可以有效改善慢性乙肝患者的肝功能和病情。

    【关键词】慢性乙型肝炎；心理干预；肝功能；乙肝表面抗原

    【Abstract】Objective：To study the effect of psychological intervention on chronic hepatitis B patient's liver function and pathogenetic condition.Methods：The intervention group(59 patients)accepted psychological intervention plus medication while the control group(49 patients) accepted only routine medication.Each group was tested liver functions and hepatitis B virus surface antigen (HBsAg) before and after intervention, and then found out the effect of psychological intervention by comparing the test result.Results：There were non-significant difference between the two groups in liver function and the HBsAg before psychological intervention. While after intervention, the two groups showed significant difference in ALT,AST,ALB and HbsAg.Conclusion：It's effective to improve chronic B liver sufferer's liver function and HBsAg by routine medication plus psychological intervention. ......