短暂性脑缺血发作患者ABCD2评分与脑动脉狭窄关系分析
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【摘要】目的 探讨短暂性脑缺血发作(transient ischemic attack，TIA)患者ABCD2评分和脑动脉狭窄的关系。 方法 回顾性分析了68例TIA患者ABCD2评分和颅脑磁共振血管成像(magnetic resonance angiography，MRA)的影像资料，依据ABCD2评分分为≥4分组和≤3分组，依据MRA评估分为动脉狭窄≥50%组和<50%组，探讨ABCD2评分与脑动脉狭窄的相关性。 结果ABCD2评分分为≥4分组和≤3分组比较，动脉狭窄≥50%的比率增高(73.3% vs 42.1%，p<0.005)；既往有卒中、高血压、冠心病、高脂血症、糖尿病病史的患者比率增高(p<0.05)；ABCD2评分分为≥4分组和≤3分组比较，TIA后7天内卒中发生率增高(13.3% vs 2.63%,P<0.05)。 结论 ABCD2评分≥4分的TIA患者MRA显示颅内动脉狭窄率高，且在TIA后7天内发生卒中的风险增高。
【关键词】脑缺血发作，短暂性；ABCD2评分；磁共振血管造影术
Analysis of the Relationship between ABCD2 score and Cerebral Artery Stenosis in Transient Ischemic Attack Patients
SHAN Zhi-yuan
Department of Neurology, Zhumadian Central Hospital, Zhumadian 463000, China
【Abstract】Objective To determine the relationship between ABCD2 score and cerebral artery stenosis of patients with transient ischemic attack(TIA). Methods We retrospectively reviewed medical records of 68 patients with TIA；all of them were examined with the magnetic resonance angiography(MRA).All patients were divided into two groups according to ABCD2 score ≥4 point or not, and cerebral artery stenosis ≥50% or not. The relationship between ABCD2 score and cerebral artery stenosis was analyzed. Results Group ABCD2 score ≥4 point were more likely to have cerebral artery stenosis ≥50% compared with group ABCD2 score ≤3 point(73.3% vs 42.1%,p<0.005). Group ABCD2 score ≥4 point were more likely to have stroke history, hypertension, diabetes and hyperlipemia than those score ≤3 point (p<0.05).The stroke within 7 days after TIA is higher in group ABCD2 score ≥4 point than that in group ABCD2 score ≤3 point (13.3% vs 2.63%,p<0.05). Conclusion The patients with ABCD2 score ≥4 point show higher rate of cerebral artery stenosis. The stroke within 7 days after TIA is higher in patients with ABCD2 score ≥4 point.
【Key Words】Ischemic attack, transient；ABCD2 score；Magnetic resonance angiography
短暂性脑缺血发作(transient ischemic attack, TIA)后近期卒中的发生率较高，对其预后的评估有重要意义，自2000年开始先后应用了加利福尼亚评分、ABCD评分、ABC D2评分评估TIA的预后[1]，但ABCD2评分评估预后的机制研究较少。本研究应用ABCD2评分和磁共振血管成像(magnetic resonance angiography ......
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