瑞格列奈治疗2型糖尿病临床疗效观察
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[摘要] 目的 观察瑞格列奈治疗2型糖尿病的临床疗效。 方法 选择52例糖尿病患者随机分为治疗组(瑞格列奈单独用药组)22例,对照组(瑞格列奈与二甲双胍联合用药组)30例。治疗组给予瑞格列奈1.5 mg/d,,对照在治疗组的基础上再给予二甲双胍7.5 mg/d,连续治疗12周,比较两组治疗前后的空腹血糖,餐后2 h血糖和糖化血红蛋白等变化,并记录药物的不良反应。 结果 两组治疗后FBG、2hPBG、HbAlc等较治疗前均有下降,差异有统计学意义(P<0.05)。且未观察到药物有明显的不良反应。 结论 瑞格列奈无论单独应用还是联合用药,治疗糖尿病临床疗效好且安全性高,效果理想。
[关键词] 瑞格列奈;二甲双胍;2型糖尿病
[中图分类号] R587.1 [文献标识码] A [文章编号] 2095-0616(2012)05-56-02
Observation on the clinical curative effect of Repaglinide in treating type 2 diabetes mellitus
GONG Ying LIU Jian
Department of Pharmacy, Fourth People's Hospital of Ji'nan City, Ji'nan 250031,China
[Abstract] Objective To observe the Repaglinide in treating type 2 diabetes mellitus clinical curative effect. Methods The hospital in 52 cases of diabetes was randomly divided into the treatment group of the Repaglinide alone medication group of 22 cases. The control group of Repaglinide and malformed combined medication group of 30 cases, the treatment group were treated with Repaglinide in 1 ......
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