氨甲环酸治疗黄褐斑临床疗效观察(1)
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[摘要] 目的 观察口服氨甲环酸治疗黄褐斑的临床疗效及不良反应。 方法 将96例患者随机分为治疗组和对照组两组，治疗组54例，氨甲环酸1.0 g/d，外用4%氢醌共12周；对照组42例，维生素C 1.2 g/d， 外用4%氢醌12周，分别于治疗结束及结束后12周观察疗效及不良反应。 结果 12周及24周时治疗组有效率为57.4%及51.9%，对照组有效率35.7%及28.6%，12周及24周时两组疗效比较差异均有统计学意义(P<0.05)，未见明显不良反应。 结论 氨甲环酸治疗黄褐斑安全有效。
[关键词] 黄褐斑；氨甲环酸；临床疗效
[中图分类号] R758.4+2 [文献标识码] B [文章编号] 2095-0616(2012)05-76-02
Clinical efficacy of tranexamic acid in the treatment of chloasma
LI Xia
Department of Dermatology, Chinese Medicine Hospital of Jurong City in Jiangsu Province , Jurong 212400,China
[Abstract] Objective To probe furthenly the effect and adverse reactions of tranexamic acid on treating chloasma through clinical study.Methods All of cases was devided into treatment group and control group.The treatment group (54) was given tranexamic acid and hydroquinone,and the control group (42) was given Vitamin C and hydroquinone ......
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