头孢美唑钠治疗成年人下呼吸道感染40例疗效分析
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[摘要] 目的 评价国产头孢美唑钠治疗成年人下呼吸道感染的临床疗效和安全性。 方法 用头孢美唑钠治疗40例下呼吸道感染的成年患者，1 g，ivgtt，q12 h，疗程7～14 d。观察细菌性疗效、细菌清除率及不良反应。 结果 临床有效率为85.0%(34/40)，细菌清除率为76.9%(20/26)，无明显不良反应。 结论 头孢美唑钠治疗成年人下呼吸道感染疗效性好、安全性高。
[关键词] 头孢美唑钠；下呼吸道感染；疗效
[中图分类号] R562.1?[文献标识码] B?[文章编号] 2095-0616(2012)12-54-02
Effect analysis of treating 40 cases of adults lower respiratory tract infection with cefmetazole
GAN?Liyuan
Department of Internal Medicine,Chongqing Chang''an Hospital，Chongqing 400023,China
[Abstract] Objective To evaluate the efficacy and safety of domestic cefmetazole in the treatment of the lower respiration tract infection in the adults. Methods 40 patients with lower respirationg tract infection had accepted the treatment of cefmetazole.Drugs ard administered two times a day for 7～14 days,at a daily does of 2 g. Results The overall effective rate of cefmetazole was 85%(34/40).The bacterial clearance rate was 83.3%(25/30).No obvious adverse reactions were observed in these patients. Conclusion Cefmetazole is an effective and safe antibacterial agent in the treatment of the lower respiration tract in the adults.
[Key words] Cefmetazole;Lower respirationg tract infection;Effect
头孢美唑钠系第二代头孢霉素类半合成抗生素，其抗菌谱广，对β-内酰胺酶稳定,对多种革兰阳性菌、革兰阴性菌及厌氧菌均有抗菌作用，对葡萄球菌、大肠杆菌、克雷伯杆菌、变形杆菌等有良好的抗菌作用，本品的耐酶性能强[1]。笔者用头孢美唑钠治疗40例成年人下呼吸道感染患者，取得较好疗效，现报道如下。
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