王田杨 戴高中

    [摘要]近年来肠道微生态得到人们的关注，而对胃内菌群的研究仅停留在幽门螺杆菌(Hp)的基础上。随着分子生物学技术以及16S rDNA 技术的出现，胃内微生态被揭开神秘的面纱。近年来已有少量研究发现，胃内微生态与胃癌的发生及发展息息相关，包括幽门螺杆菌、胃内其他菌群、放线菌、真菌、病毒等，都可通过多种机制，导致胃癌的发生或者进展。Hp 如同导火索，揭开了胃内微生态与胃癌这场战役的序幕。本文探究胃内微生态与胃癌的机制，为今后胃微生态以及胃癌的研究提供理论基础以及参考依据。

    [关键词]微生态;胃癌;细菌;病毒;真菌

    [中图分类号] R692? [文献标识码] A? [文章编号]2095-0616(2021)24-0058-04

    Research progress of gastric microecology and gastric cancer

    WANGTianyang1，2DAIGaozhong

    1.Graduate School， Nanjing University of Chinese Medicine， Jiangsu， Nanjing 210023， China;2. Department of Gastroenterology， Wuxi Traditional Chinese Medicine Hospital， Jiangsu， Wuxi 214071， China

    [Abstract] In recent years， the intestinal microecology has been widely concerned， while the research on the flora in the stomach is limited to Helicobacter pylori (Hp). With the emergence of molecular biology technology and 16S rDNA technology， the micro-ecology in the stomach has been unveiled. Recently， some studies have found that gastric microecology is closely related to the occurrence and development of gastric cancer， including Hp， other flora in the stomach ......