杨琅晶 邹爱容 杨鸣春

    [摘要]缺血性脑卒中具有高发病率、高致残率、高致死率、高复发率、高经济负担的特点，为患者家庭及社会带来沉重负担，静脉溶栓是急性缺血性脑卒中患者唯一被批准的全身再灌注治疗方式，是急性脑卒中管理的基石。然而，静脉溶栓后患者的获益情况因人而异，静脉溶栓后患者发生早期神经功能改善(ENI)是国内外研究者关注的热点，大量研究表明关于急性缺血性脑卒中静脉溶栓后发生ENI的因素各不相同。因此，临床医护人员早期识别和评估静脉溶栓后患者发生ENI的相关因素，对促进患者的转归具有重要意义。本文就急性缺血性脑卒中静脉溶栓后患者发生ENI的因素进行综述。

    [关键词]急性缺血性脑卒中;静脉溶栓;早期神经功能改善;相关因素

    [中图分类号]R743.3? [文献标识码]A? [文章编号]2095-0616(2022)05-0044-05

    Advances in the study of early neurological improvement occurring after intravenous thrombolysis

    YANG Langjing1? ZOU Airong2? YANG Mingchun2

    1. School of Nursing，Yunnan University of Chinese Medicine，Yunnan，Kunming 650504，China;2. Department of Internal Medicine，Yan'an Hospital Affiliated to Kunming Medical University，Yunnan，Kunming 650051，China

    [Abstract] Ischemic stroke is characterized by high incidence，high disability，high mortality，high relapse rate，and high economic burden，which brings a heavy burden to patients’families and society. Intravenous thrombolysis (IVT)is the only approved systemic reperfusion therapy for patients with acute ischemic stroke (AIS)and the cornerstone of acute stroke management. However ......