陈圆 陈光辉

    [摘要]癫痫作为常见神经系统疾病，在我国具有高发病率、高致残率及高病死率的特点。50%的癫痫患者有轻度以上的情感障碍。未加干预的情感障碍可能成为患者生活质量降低甚至自杀的高危因素。本研究将从原发病癫痫及其癫痫伴发情感障碍的可能机制、危险因素、治疗方案的研究进展进行综述。

    [关键词]癫痫;抑郁;焦虑;发病率

    [中图分类号] R742.1;R749.4? [文献标识码] A? [文章编号]2095-0616(2022)09-0066-04

    Research progress of affective disorder in patients with epilepsy

    CHEN? Yuan? CHEN? Guanghui

    Department of Neurology， the Shiyan Renmin Hospital， Hubei University of Medicine， Hubei， Shiyan 442000， China [Abstract] As a common neurological disease， epilepsy has the characteristics of high incidence， high disability rate and high mortality rate in our country.50% of people with epilepsy have more than mild affective disorder. Unintervened affective disorder may be a high risk factor for patients with reduced quality of life or even suicide. This article reviews the research progress on the possible mechanism， risk factors and treatment of primary epilepsy and its associated affective disorder.

    [Key words] Epilepsy; Depression; Anxiety; Incidence

    癲痫是一种反复发作的慢性神经系统疾病。流行病学显示，中国约有960万人患有癫痫，每年约有40万新发病例[1-2]。50%以上的患者有轻度以上的情绪障碍[3] ......