祛风散寒除湿中药正清风痛宁缓释片对小鼠软骨细胞TGF—β、IL—1β、Fstl—1、TIMP—3表达水平的影响(2)
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(P > 0.05)；the mRNA expressions of TIMP-3 of the S100，S50，S25 groups were significantly higher than that of the model control group (P < 0.01)，while comparing the S100，S25group with the model control group，the difference was not statistically significant (P > 0.05).Conclusion：This experimental study demonstrated that Chinese medicine with effects of expelling wind，removing cold and eliminating dampness had a protective effect on articular cartilage，which might realize by the expression of TGF-β，Fstl-1 and TIMP-3 in cartilage cells and down-regulating the expression of inflammatory disease factor IL-1β ......
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