Wnt信号通路及其抑制剂Dickkopf-1在骨关节炎中的作用探讨(4)
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[28] CAO Z,LIU R,ZHANG H,et al.Osterix controls cementoblast differentiation through downregulation of Wnt-signaling via enhancing DKK1 expression[J].Int J Biol Sci,2015,11(3):335-344.
[29] LIU Y,JU JZ,ZHANG W,et al.Construction of DKKl-siRNA eukaryotic expression vectors and the therapeutic effect on osteoporotic rats[J].Chinese Journal of Osteoporosis,2015,21(2):125-131,151.
[30] WANG FS,KO JY,LIN CL,et al.Knocking down dickkopf-1 alleviates estrogen deficiency induction of bone loss:a histomor pholosical study in ovariectomized rats[J].Bone,2007,40(2):485-492.
[31] GLANTSCHNIG H,HAMPTON R,WEI N,et al.Fully human anti DKK1 attobodies incrcase Bone formation and resolve osteopenia in mouse modles of estrogen-deficiency iduced bone loss[J].J Bone Miner Res,2008,23(Suppl 1):S60-S61.
[32] RAY S,KHASSAWNA TE,SOMMER U,et al.Differences in expression of Wnt antagonist Dkk1 in healthy versus pathological bone samples[J].J Microsc,2017,265(1):111-120., 百拇医药(樊梅 唐芳 马武开 兰维娅 李宇 蒋总 蔡鑫)