【摘要】目的 观察缬沙坦联合氢氯噻嗪治疗原发性高血压的疗效。方法 将323例原发性高血压患者随机分为研究组162例和对照组161例。两组均予心理疏导、病因解释、介绍治疗方法等临床常规宣教。对照组给予氢氯噻嗪缓释片口服治疗，研究组在此基础上给予缬沙坦口服治疗。2个疗程后观察两组血压改善情况。结果 治疗后，两组收缩压和舒张压水平均降低，且研究组收缩压和舒张压均低于对照组，差异均有统计学意义(P<0.05)。结论 缬沙坦联合氢氯噻嗪治疗原发性高血压疗效显著，可明显降低血压水平，优于单一药物，具有临床推广价值。

    【关键词】高血压；原发性；缬沙坦；氢氯噻嗪

    【中图分类号】R544.1 【文献标识码】B

    【Abstract】Objective To observe the curative effect of valsartan combined with hydrochlorothiazide in treatment of essential hypertension.Methods 323 patients with primary hypertension were randomly divided into study group 162 cases and control group of 161 cases.The 2 groups were given psychological counseling ......