高盐饮食对大鼠高血压肾病进展的影响(2)
结合本实验研究结果及相关文献,得出结论,长期持续的高盐饮食使尿微量白蛋白、尿蛋白、血肌酐等高血压肾病相关指标显著增高,证明了高盐摄入对高血压肾病的发展有一定的促进作用,所以对高血压患者在控制血压之余再限制钠盐的摄入量是必要的。
参考文献
[1]Bi Z, Liang X, Xu A, et al. Hypertension Prevalence,Awareness, Treatment, and Control and Sodium Intake in Shandong Province,China: Baseline Results From Shandong-Ministry of Health Action on Salt Reduction and Hypertension (SMASH), 2011[J]. Prev Chronic Dis, 2014,11:E88.
[2]Donghai Y, .Arndt P, Uta K, et al. Urinary podocyte loss is a more specific marker of ongoing glomerular damage than proteinuria. J Am Soc Nephrol 1b:1733-1741.
[3]Weinberger MH. Sodium and blood pressure 2003 [J]. Curr Opin Cardiol,2004,19:353-356.
[4]Iwamoto T,Kita S,Katsuragi T. Salt-sensitive hypertension, Na + / Ca2 + exchanger,and vascular smooth muscle[J]. Trends Cardiovasc Med,2005,15(8):273-277.
[5]Daisuke Nakano,Hiroyuki Kobori,James L. Burford.Multiphoton Imaging of the Glomerular Permeability of Angiotensinogen. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY.2012,5(4):564.
[6]Habibi J,Hayden M R,Ferrario C M, et al. Salt Loading Promotes Kidney Injury via Fibrosis in Young Female Ren2 Rats[J]. Cardiorenal Med,2014,4(1):43-52.
[7]朱國献,谭毅华,李 涛.HIF-1α及VEGF基因促进大鼠缺血组织血管新生的实验研究[J].深圳中西医结合杂志,2016,5(18):545., 百拇医药(庞磊 姚春颖 林玲)
参考文献
[1]Bi Z, Liang X, Xu A, et al. Hypertension Prevalence,Awareness, Treatment, and Control and Sodium Intake in Shandong Province,China: Baseline Results From Shandong-Ministry of Health Action on Salt Reduction and Hypertension (SMASH), 2011[J]. Prev Chronic Dis, 2014,11:E88.
[2]Donghai Y, .Arndt P, Uta K, et al. Urinary podocyte loss is a more specific marker of ongoing glomerular damage than proteinuria. J Am Soc Nephrol 1b:1733-1741.
[3]Weinberger MH. Sodium and blood pressure 2003 [J]. Curr Opin Cardiol,2004,19:353-356.
[4]Iwamoto T,Kita S,Katsuragi T. Salt-sensitive hypertension, Na + / Ca2 + exchanger,and vascular smooth muscle[J]. Trends Cardiovasc Med,2005,15(8):273-277.
[5]Daisuke Nakano,Hiroyuki Kobori,James L. Burford.Multiphoton Imaging of the Glomerular Permeability of Angiotensinogen. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY.2012,5(4):564.
[6]Habibi J,Hayden M R,Ferrario C M, et al. Salt Loading Promotes Kidney Injury via Fibrosis in Young Female Ren2 Rats[J]. Cardiorenal Med,2014,4(1):43-52.
[7]朱國献,谭毅华,李 涛.HIF-1α及VEGF基因促进大鼠缺血组织血管新生的实验研究[J].深圳中西医结合杂志,2016,5(18):545., 百拇医药(庞磊 姚春颖 林玲)