吸烟与腰椎间盘突出症手术疗效关系的研究(2)
吸烟者对腰背痛的影响近年来收到国内外学者的广泛关注。结合大量文献[2-3],我们推测认为吸烟与腰痛的关系的机制可能是:吸烟增加增加腰椎间盘的压力;吸烟减少骨矿物质含量吸烟损害纤维蛋白溶解作用,并增加纤维沉积和瘢痕形成;吸烟减少椎体血流量,从而影响椎间盘代谢平衡;可以导致动脉血流不足导致受压的神经根缺血引起疼痛。
本研究发现抑郁评分越高,疼痛程度及功能障碍程度越高。Alschuler等[4]在一项对明30名慢性腰痛的患者研究中,发现60%的患者有抑郁症状。Ohayon等[5]报道18%的慢性腰痛患者有抑郁症状。这些研究表明,在慢性腰痛患者中抑郁等精神心理因素值得关注。综上所述,吸烟是影响腰椎间盘突出症手术预后因素,吸烟不但导致患者抑郁评分增加,并且能影响手术疗效。
参考文献
[1]Kerns RD, Sellinger J, Goodin BR (2011) Psychological treatment of chronic pain. Annu Rev Clin Psychol 7:411–434
[2] Susan CS , Mark SG,Nancy EM, et al . The association between cigarette smoking and back pain in adultsJ . Spine ,1999 ,24 :1090 ~1098.
[3]Marks G, Susanc S, Nlancy EM. A review of the association between cigarette cohort smoking and the development of nonspecific back[J].Spine,2000,25:995~1014.
[4]Alschuler KN, Theisen-Goodvich ME, Haig AJ, Geisser ME(2008) A comparison of the relationship between depression,perceived disability, and physical performance in persons withchronic pain. Eur J Pain 12(6):757–764
[5].Ohayon MM, Schatzberg AF (2010) Chronic pain and major depressive disorder in the general population. J Psychiatr Res44(7):454–461, 百拇医药(欧颖)
本研究发现抑郁评分越高,疼痛程度及功能障碍程度越高。Alschuler等[4]在一项对明30名慢性腰痛的患者研究中,发现60%的患者有抑郁症状。Ohayon等[5]报道18%的慢性腰痛患者有抑郁症状。这些研究表明,在慢性腰痛患者中抑郁等精神心理因素值得关注。综上所述,吸烟是影响腰椎间盘突出症手术预后因素,吸烟不但导致患者抑郁评分增加,并且能影响手术疗效。
参考文献
[1]Kerns RD, Sellinger J, Goodin BR (2011) Psychological treatment of chronic pain. Annu Rev Clin Psychol 7:411–434
[2] Susan CS , Mark SG,Nancy EM, et al . The association between cigarette smoking and back pain in adultsJ . Spine ,1999 ,24 :1090 ~1098.
[3]Marks G, Susanc S, Nlancy EM. A review of the association between cigarette cohort smoking and the development of nonspecific back[J].Spine,2000,25:995~1014.
[4]Alschuler KN, Theisen-Goodvich ME, Haig AJ, Geisser ME(2008) A comparison of the relationship between depression,perceived disability, and physical performance in persons withchronic pain. Eur J Pain 12(6):757–764
[5].Ohayon MM, Schatzberg AF (2010) Chronic pain and major depressive disorder in the general population. J Psychiatr Res44(7):454–461, 百拇医药(欧颖)
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