1.3 Hepatitis E virus

    HEVis a single-stranded positive-sense RNA genome which encodes3open reading frames ORF1，ORF2，ORF3.The generation of N-terminal truncated virus-like particles have identified3definitive domains，S，M，and P domain.The E2s domain of the capsid protein(pro) has been identified as the major immune target.Recent study shows another enveloped types of HEV.The envelop only includs the phospholipid bilayer membrane.Thus ......