右佐匹克隆辅助治疗中老年女性高血压合并睡眠障碍的疗效观察(1)
摘要 目的：探讨右佐匹克隆辅助治疗中老年女性高血压合并睡眠障碍的临床疗效。方法：选择2015年1月至2017年2月我院就诊86例中老年女性高血压合并睡眠障碍患者随机分为观察组(43例)和对照组(43例)，对照组给予常规降压与安慰剂治疗，观察组给予常规降压与右佐匹克隆辅助治疗。结果：治疗后观察组收缩压低于对照组，差异有统计学意义(P<0.05)，而舒张压2组无明显差异(P>0.05)。观察组治疗后睡眠障碍总有效率为83.72%，对照组为39.53%，观察组高于对照组(P<0.05)，观察组睡眠质量评分低于对照组(P<0.05)。结论：右佐匹克隆辅助治疗中老年女性高血压合并睡眠障碍效果较好，可明显改善患者睡眠质量，值得推广。
关键词 右佐匹克隆；高血压；睡眠障碍
中图分类号：R544.1；R749.1+6文献标识码：A文章编号：20957130(2017)05263266
Effect of Adjuvant Therapy on Hypertension Associated with Sleep Disorder in Middleaged and Elderly Women
Han Guangquan
(Cangping Beiqijia Community Health Service Center， Beijing，102209)
Abstract Objective：To investigate the clinical efficacy of right handed adjunctive therapy for middle aged and elderly women with hypertension combined with sleep disorder. Methods：86 cases in middleaged and elderly women in hypertensive patients with sleep disorders were randomly divided into observation group (43 cases) and control group (43 cases)， from January 2015 to February 2017.The control group was given routine antihypertensive and placebo treatment， the observation group was given routine antihypertensive and zopiclone. Results：After treatment， the systolic blood pressure of the observation group was lower than that of the control group， the difference was statistically significant (P<0.05)， but there was no significant difference in diastolic blood pressure between the two groups (P>0.05). The total effective rate of sleep disturbance after treatment was 83.72% in the observation group and 39.53% in the control group. The observation group was higher than that in the control group (P<0.05)， and the sleeping quality score in the observation group was lower than that in the control group (P<0.05). Conclusion：It is effective to treat hypertension and sleep disorders in middleaged and elderly women with right and wrong， which can significantly improve the quality of sleep and lower blood pressure， worth popularizing.
Key Words Right handed clone； Hypertension； Sleep disorders
據研究，雌激素对心血管系统具有保护作用[1]，女性在绝经前，高血压的发病率低于男性，但在绝经后收缩压水平明显高于男性[2]。中老年女性由于内分泌的变化，失眠、高血压、焦虑症等疾病的发病率明显上升。高血压本身可导致睡眠障碍，而长期失眠又可引起焦虑、抑郁情绪、记忆力下降，还可诱发高血压或导致血压不稳，进而导致心血管疾病、肾脏疾病等[3]。右佐匹克隆作为一种镇静催眠药，具有催眠效果好、安全性高、无成瘾性等特点，而在失眠的治疗中应用较为广泛。我院将该药物纳入对中老年女性高血压合并睡眠障碍患者的治疗，本文对其效果进行分析。
1 资料与方法
1.1 一般资料 选择我院从2015年1月至2017年2月收治的86例中老年女性高血压合并睡眠障碍患者。睡眠障碍的诊断符合《中国精神障碍分类与诊断标准》中关于失眠症的诊断标准，所有患者均未合并严重心、肝、肾功能疾患、继发性高血压及严重精神疾患。86例患者随机分为观察组和对照组，每组各43例。观察组43例中，年龄46～73岁，平均年龄(63.71±3.09)岁，高血压病程5～21年，平均病程(8.32±1.42)年，睡眠障碍病程2～12年，平均病程(5.73±1.08)年；对照组43例中，年龄46～72岁，平均年龄(63.03±3.24)岁，高血压病程4～22年，平均病程(8.96±1.33)年，睡眠障碍病程2～13年，平均病程(5.91±1.12)年。2组患者性别、年龄等差异无统计学意义(P>0.05)。, 百拇医药(憨广泉)
关键词 右佐匹克隆；高血压；睡眠障碍
中图分类号：R544.1；R749.1+6文献标识码：A文章编号：20957130(2017)05263266
Effect of Adjuvant Therapy on Hypertension Associated with Sleep Disorder in Middleaged and Elderly Women
Han Guangquan
(Cangping Beiqijia Community Health Service Center， Beijing，102209)
Abstract Objective：To investigate the clinical efficacy of right handed adjunctive therapy for middle aged and elderly women with hypertension combined with sleep disorder. Methods：86 cases in middleaged and elderly women in hypertensive patients with sleep disorders were randomly divided into observation group (43 cases) and control group (43 cases)， from January 2015 to February 2017.The control group was given routine antihypertensive and placebo treatment， the observation group was given routine antihypertensive and zopiclone. Results：After treatment， the systolic blood pressure of the observation group was lower than that of the control group， the difference was statistically significant (P<0.05)， but there was no significant difference in diastolic blood pressure between the two groups (P>0.05). The total effective rate of sleep disturbance after treatment was 83.72% in the observation group and 39.53% in the control group. The observation group was higher than that in the control group (P<0.05)， and the sleeping quality score in the observation group was lower than that in the control group (P<0.05). Conclusion：It is effective to treat hypertension and sleep disorders in middleaged and elderly women with right and wrong， which can significantly improve the quality of sleep and lower blood pressure， worth popularizing.
Key Words Right handed clone； Hypertension； Sleep disorders
據研究，雌激素对心血管系统具有保护作用[1]，女性在绝经前，高血压的发病率低于男性，但在绝经后收缩压水平明显高于男性[2]。中老年女性由于内分泌的变化，失眠、高血压、焦虑症等疾病的发病率明显上升。高血压本身可导致睡眠障碍，而长期失眠又可引起焦虑、抑郁情绪、记忆力下降，还可诱发高血压或导致血压不稳，进而导致心血管疾病、肾脏疾病等[3]。右佐匹克隆作为一种镇静催眠药，具有催眠效果好、安全性高、无成瘾性等特点，而在失眠的治疗中应用较为广泛。我院将该药物纳入对中老年女性高血压合并睡眠障碍患者的治疗，本文对其效果进行分析。
1 资料与方法
1.1 一般资料 选择我院从2015年1月至2017年2月收治的86例中老年女性高血压合并睡眠障碍患者。睡眠障碍的诊断符合《中国精神障碍分类与诊断标准》中关于失眠症的诊断标准，所有患者均未合并严重心、肝、肾功能疾患、继发性高血压及严重精神疾患。86例患者随机分为观察组和对照组，每组各43例。观察组43例中，年龄46～73岁，平均年龄(63.71±3.09)岁，高血压病程5～21年，平均病程(8.32±1.42)年，睡眠障碍病程2～12年，平均病程(5.73±1.08)年；对照组43例中，年龄46～72岁，平均年龄(63.03±3.24)岁，高血压病程4～22年，平均病程(8.96±1.33)年，睡眠障碍病程2～13年，平均病程(5.91±1.12)年。2组患者性别、年龄等差异无统计学意义(P>0.05)。, 百拇医药(憨广泉)
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