慢性气道疾病合并失眠症诊治研究进展(3)
[5]Luyster FS，Buysse DJ，Strollo PJ Jr.Comorbid insomnia and obstructive sleep apnea：challenges for clinical practice and research[J].J Clin Sleep Med，2010，6(2)：196204.
[6]Eysteinsdottir B，Gislason T，Pack AI，et al.Insomnia complaints in lean patients with obstructive sleep apnea negatively affect positive airway pressure treatment adherence[J].J Sleep Res，2017，26(2)：159165.
[7]Krell SB，Kapur VK.Insomnia complaints in patients evaluated for obstructive sleep apnea[J].Sleep Breath，2005，9(3)：104110.
, http://www.100md.com
[8]Dolly FR，Block AJ.Effect of flurazepam on sleepdisordered breathing and nocturnal oxygen desaturation in asymptomatic subjects[J].Am J Med，1982，73(2)：239243.
[9]Bezel R，Russi E，Kronauer H，et al.Lifethreatening apnea after midazolam administration in a patient with obstructive sleep apnea syndrome[J].Schweiz Med Wochenschr，1987，117(15)：579583.
[10]Zhang XJ，Li QY，Wang Y，et al.The effect of nonbenzodiazepine hypnotics on sleep quality and severity in patients with OSA：a metaanalysis[J].Sleep Breath，2014，18(4)：781789.
, 百拇医药
[11]Gooneratne NS，Gehrman P，Gurubhagavatula I，et al.Effectiveness of ramelteon for insomnia symptoms in older adults with obstructive sleep apnea：a randomized placebocontrolled pilot study[J].J Clin Sleep Med，2010，6(6)：572580.
[12]Krakow B，Melendrez D，Lee SA，et al.Refractory insomnia and sleepdisordered breathing：a pilot study[J].Sleep Breath，2004，8(1)：1529.
[13]Budhiraja R，Roth T，Hudgel DW，et al.Prevalence and polysomnographic correlates of insomnia comorbid with medical disorders[J].Sleep，34(7)：859867.
, http://www.100md.com
[14]Xiang YT，Wong TS，Tsoh J，et al.Insomnia in older adults with chronic obstructive pulmonary disease(COPD)in Hong Kong：a casecontrol study[J].COPD，2014，11(3)：319324.
[15]Budhiraja R，Parthasarathy S，Budhiraja P，Habib MP，Wendel C，Quan SF.Insomnia in patients with COPD[J].Sleep，2012，35(3)：369375.
[16]Zhou Y，Wang X，Zeng X，et al.Positive benefits of theophylline in a randomized，doubleblind，parallelgroup，placebocontrolled study of lowdose，sleeprelease theophylline in the treatment of COPD for 1 year[J].Respirology，2006，11(5)：603610.
, 百拇医药
[17]Rogliani P，Calzetta L，Cazzola M，et al.Drug safety evaluation of roflumilast for the treatment of COPD：a metaanalysis[J].Expert Opin Drug Saf，2016，15(8)：11331146.
[18]Hynninen MJ，Pallesen S，Hardie J，et al.Insomnia symptoms，objectively measured sleep，and disease severity in chronic obstructive pulmonary disease outpatients[J].Sleep Med，14(12)：13281333., 百拇医药(张秀娟 李庆云)
[6]Eysteinsdottir B，Gislason T，Pack AI，et al.Insomnia complaints in lean patients with obstructive sleep apnea negatively affect positive airway pressure treatment adherence[J].J Sleep Res，2017，26(2)：159165.
[7]Krell SB，Kapur VK.Insomnia complaints in patients evaluated for obstructive sleep apnea[J].Sleep Breath，2005，9(3)：104110.
, http://www.100md.com
[8]Dolly FR，Block AJ.Effect of flurazepam on sleepdisordered breathing and nocturnal oxygen desaturation in asymptomatic subjects[J].Am J Med，1982，73(2)：239243.
[9]Bezel R，Russi E，Kronauer H，et al.Lifethreatening apnea after midazolam administration in a patient with obstructive sleep apnea syndrome[J].Schweiz Med Wochenschr，1987，117(15)：579583.
[10]Zhang XJ，Li QY，Wang Y，et al.The effect of nonbenzodiazepine hypnotics on sleep quality and severity in patients with OSA：a metaanalysis[J].Sleep Breath，2014，18(4)：781789.
, 百拇医药
[11]Gooneratne NS，Gehrman P，Gurubhagavatula I，et al.Effectiveness of ramelteon for insomnia symptoms in older adults with obstructive sleep apnea：a randomized placebocontrolled pilot study[J].J Clin Sleep Med，2010，6(6)：572580.
[12]Krakow B，Melendrez D，Lee SA，et al.Refractory insomnia and sleepdisordered breathing：a pilot study[J].Sleep Breath，2004，8(1)：1529.
[13]Budhiraja R，Roth T，Hudgel DW，et al.Prevalence and polysomnographic correlates of insomnia comorbid with medical disorders[J].Sleep，34(7)：859867.
, http://www.100md.com
[14]Xiang YT，Wong TS，Tsoh J，et al.Insomnia in older adults with chronic obstructive pulmonary disease(COPD)in Hong Kong：a casecontrol study[J].COPD，2014，11(3)：319324.
[15]Budhiraja R，Parthasarathy S，Budhiraja P，Habib MP，Wendel C，Quan SF.Insomnia in patients with COPD[J].Sleep，2012，35(3)：369375.
[16]Zhou Y，Wang X，Zeng X，et al.Positive benefits of theophylline in a randomized，doubleblind，parallelgroup，placebocontrolled study of lowdose，sleeprelease theophylline in the treatment of COPD for 1 year[J].Respirology，2006，11(5)：603610.
, 百拇医药
[17]Rogliani P，Calzetta L，Cazzola M，et al.Drug safety evaluation of roflumilast for the treatment of COPD：a metaanalysis[J].Expert Opin Drug Saf，2016，15(8)：11331146.
[18]Hynninen MJ，Pallesen S，Hardie J，et al.Insomnia symptoms，objectively measured sleep，and disease severity in chronic obstructive pulmonary disease outpatients[J].Sleep Med，14(12)：13281333., 百拇医药(张秀娟 李庆云)