摘要 目的：探讨5-FU联合奥沙利铂方案治疗配合综合护理在晚期转移性小肠癌中的效果。方法：选取2018年7月至2019年6月来雷州仁康医院接受治疗的晚期转移性小肠癌患者88例作为研究对象，按照患者的病床号码将患者分为对照组和观察组，每组44例。对2组患者晚期转移性小肠癌患者分别给予常规护理和综合性护理。结果：观察组对疾病控制的有效率为72.73%，整体上病情比对照组控制地更好(P<0.05);观察组护理后的睡眠质量、入睡时间和睡眠时间得分分别为(1.34±0.27)分、(1.41±0.30)分和(1.18±0.29)分，均明显比对照组的得分低(P<0.05)。结论：5-FU联合奥沙利铂方案治疗配合综合护理应用于晚期转移性小肠癌疗效好，可改善睡眠质量。

    关键词 5-FU;奥沙利铂;综合护理;晚期转移性小肠癌;睡眠质量

    Abstract Objective：To explore the effect of 5-fu combined oxaliplatin regimen combined with comprehensive nursing in advanced metastatic small bowel cancer.Methods：Eighty-eight patients with advanced metastatic small bowel cancer who were treated at Leikang Renkang Hospital from July 2018 to June 2019 were enrolled. The patients were divided into control group and observation group according to the patient's bed number ......